Full
Outline
The objective of this study was to evaluate the clinical benefit of Modified Shenling Baizhu Powder（参苓白术散加减）in the treatment of acne.
From January 2020 to December 2022，120 patients with acne vulgaris were selected as participants in the Dermatology Outpatient Department of Lishui Hospital of Traditional Chinese Medicine.All patients were divided into two groups according to the difference of single and even numbers in the order of treatment.The group with single number of treatment was set as the control group，and the group with even number of treatment was set as the observation group.The control group was treated with isotretinoic acid softgel combined with fusidic acid cream，while the observation group was treated with Modified Shenling Baizhu Powder on the basis of the control group.
The effective rate of the observation group was 91.67%（55/60），which was significantly higher than that of the control group（78.33%，47/60）（P<0.05）.After 6 months of treatment，there were no significant changes in red blood cell count，white blood cell count，platelet count，liver and kidney function indexes（alanine aminotransferase，aspartate aminotransferase，serum creatinine and serum urea）between the two groups（P>0.05）.The amount of pimples，papules，pustules and total lesions in the observation group were significantly lower than those in the control group（P<0.05）.The satisfaction score of the patients in observation group was significantly higher than that in control group（P<0.05）.
For the patients with moderate and below acne vulgaris，Modified Shenling Baizhu Powder can not only improve the therapeutic effect，reduce the skin lesions，but also improve the satisfaction of the patients，and shows good safety performance.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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