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Research Progress on Chemical Compositions and Pharmacological Activities of Duhuo（Angelica Pubescentis Radix）
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Cuihui BAI1, 2, Guodong HOU1, 2, Yongxia GUAN3, Xinyu HAO4, Huifen LI1, Yujie DU1, Qingzhi LIU1, Dongxiao GUO2, 3
Chinese Archives of Traditional Chinese Medicine | 2025, 43(10) : 129 - 144
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Chinese Archives of Traditional Chinese Medicine | 2025, 43(10): 129-144
• Target on National Project •
Research Progress on Chemical Compositions and Pharmacological Activities of Duhuo（Angelica Pubescentis Radix）
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Cuihui BAI1, 2, Guodong HOU1, 2, Yongxia GUAN3, Xinyu HAO4, Huifen LI1, Yujie DU1, Qingzhi LIU1, Dongxiao GUO2, 3
Affiliations
  • 1.Shandong University of Traditional Chinese Medicine，Jinan 250355，Shandong，China
  • 2.Shandong Institute for Food and Drug Control，Shandong Engineering Research Center for Standard Innovation and Quality Evaluation of TCM，Shangdong Engineering Research Center for Generic Technologies of Traditional Chinese Medicine Formula Granules，NMPA Key Laboratory for Quality Evaluation of Gelatin Products，Jinan 250101，Shandong，China
  • 3.State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine，Linyi276006，Shandong，China
  • 4.Stomatological Hospital of Shandong University，Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration，Jinan 250012，Shandong，China
Published: 2025-10-10 doi: 10.13193/j.issn.1673-7717.2025.10.026
Outline
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Duhuo（Angelica Pubescentis Radix）is the dried root of Duhuo（Angelica pubescens Maxim.f.biserrata Shan et Yuan），which is mainly distributed in Sichuan and Hubei of China，with the effects of expelling wind and removing dampness，unblocking obstruction and relieving pain in traditional Chinese medicine.A total of 420 chemical compositions have been identified from Duhuo（Angelica Pubescentis Radix），mainly including coumarins（107）and volatile oils（262）.Modern pharmacological studies show that Duhuo（Angelica Pubescentis Radix）exhibits a variety of biological activities such as analgesic effect，anti-inflammation，vascular protection，antioxidant effect，central regulation and anti-tumor effect.In this paper，the types，structures and pharmacological effects of the main chemical components of Duhuo（Angelica Pubescentis Radix）were systematically reviewed，which provided a reference for the research on quality control，biological activity，development and utilization.

Duhuo（Angelica Pubescentis Radix）  /  coumarins  /  volatile oils  /  analgesic and anti-inflammatory effect  /  antitumor effect
白翠慧, 侯国栋, 关永霞, 郝新宇, 李慧芬, 杜玉洁, 刘青芝, 郭东晓. 独活化学成分及药理作用研究进展. 中华中医药学刊, 2025 , 43 (10) : 129 -144 . DOI: 10.13193/j.issn.1673-7717.2025.10.026
Cuihui BAI, Guodong HOU, Yongxia GUAN, Xinyu HAO, Huifen LI, Yujie DU, Qingzhi LIU, Dongxiao GUO. Research Progress on Chemical Compositions and Pharmacological Activities of Duhuo（Angelica Pubescentis Radix）[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (10) : 129 -144 . DOI: 10.13193/j.issn.1673-7717.2025.10.026
Appendix
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Year 2025 volume 43 Issue 10
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doi: 10.13193/j.issn.1673-7717.2025.10.026
  • Online Date：2026-10-30
  • Published：2025-10-10
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Affiliations
    1.Shandong University of Traditional Chinese Medicine，Jinan 250355，Shandong，China
    2.Shandong Institute for Food and Drug Control，Shandong Engineering Research Center for Standard Innovation and Quality Evaluation of TCM，Shangdong Engineering Research Center for Generic Technologies of Traditional Chinese Medicine Formula Granules，NMPA Key Laboratory for Quality Evaluation of Gelatin Products，Jinan 250101，Shandong，China
    3.State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine，Linyi276006，Shandong，China
    4.Stomatological Hospital of Shandong University，Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration，Jinan 250012，Shandong，China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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