Full
Outline
Duhuo（Angelicae Pubescentis Radix）is a classic wind-dampness eliminating medicine with outstanding efficacy of eliminating wind-dampness and relieving paralysis and pain，which is widely used in the treatment of bone diseases. However，there are many varieties of Duhuo（Angelicae Pubescentis Radix）and its efficacy varies greatly，so the effectiveness of clinical use of the drug cannot be guaranteed. Standardizing the quality of Chinese herbal medicines is the basis for ensuring the safety and effectiveness of the clinical use of Duhuo（Angelicae Pubescentis Radix）. In this paper，it reviewed the current status of quality control of Duhuo（Angelicae Pubescentis Radix），pointed out the inadequacy of only using the contents of serpentin and dihydroparsinol angelic acid ester as the quality control standard，and at the same time，combined with the core concept of Quality Marker（Q-Marker），it predicted the Q-Marker from the aspects of phytopharmacology，chemical constituent peculiarities，traditional medicinal properties，the measurability of the chemical constituents，different compounding environments，different harvesting periods and preparation methods and new efficacies. The Q-Marker was used to predict the efficacy of Duhuo（Angelicae Pubescentis Radix）. The results revealed that the coumarin-like components，such as serpentin，dihydroeucalyptol angelate，isoeucalyptol，citronellolide，psoralen，eucalyptol and scopoletin，and volatile oils，such as eucalyptol methyl ether，α-myrcene alcohol，2-（diethylaminophenylmethyl）cyclohexyl alcohol，β-hydroxycaryophyllene，angelicin A and angelicin G could be used as the Q-Markers of Duhuo（Angelicae Pubescentis Radix），which provided a reference basis to set up a comprehensive and perfect quality control system for Duhuo（Angelicae Pubescentis Radix）.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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