To evaluate the effect of Jiawei Daotan Decoction(加味导痰汤)and acupoint application on lung rehabilitation in patients with acute exacerbation of chronic obstructive pulmonary disease(COPD).
A prospective controlled trial was conducted,selecting 110 patients with acute exacerbation of COPD who visited the hospital.They were randomly divided into two groups,each with 55 cases.The control group received physical therapy.The observation group received physical therapy combined with Jiawei Daotan Decoction and acupoint application.All patients were intervened for 2 weeks as a course of treatment,totally 2 courses.The therapeutic effect after two courses,the lung function indicators and inflammatory factors were evaluated before and after intervention,continuous follow-up and observation were conducted,and adverse reactions were recorded.
There was no statistically significant difference in gender,average age,average onset time,smoking history or hypertension history between the two groups(P>0.05).The total effective rate(85.45%)in the control group was lower than that in the observation group(96.36%),with a statistically significant difference(P<0.05).After intervention,the values of forced vital capacity(FVC),forced expiratory volume in one second(FEV1)and FEV1/FVCincreased in both groups(P<0.05).After intervention,the values of FVC,FEV1 and FEV1/FVC in the observation group were significantly higher than those in the control group(P<0.05).In the two groups,the serum levels of tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and C-reactive protei(CRP)after intervention decreased(P<0.05).After intervention,the serum levels of TNF-α,IL-6 and CRPin the observation group were lower than those in the control group,with statistically significant differences(P<0.05).There was no statistically significant difference in the total adverse reaction rate between the control group(16.36%)and the observation group(14.55%)(P>0.05).
The combination of Jiawei Daotan Decoction and acupoint application can improve the pulmonary rehabilitation effect during acute exacerbation of COPD,which may be related to improving lung function and inhibiting inflammatory reactions,and can be tolerated.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |