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Effects of Xuanbai Chengqi Decoction(宣白承气汤)Combined with Budesonide Formoterol Inhalant on Lung Function and Related Inflammatory Factors in Children with Rhinitis in Remission of Bronchial Asthma
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Luying XU, Ping LI, Huifen WU
Chinese Archives of Traditional Chinese Medicine | 2025, 43(6) : 200 - 203
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Chinese Archives of Traditional Chinese Medicine | 2025, 43(6): 200-203
• Platform of Provincial Project •
Effects of Xuanbai Chengqi Decoction(宣白承气汤)Combined with Budesonide Formoterol Inhalant on Lung Function and Related Inflammatory Factors in Children with Rhinitis in Remission of Bronchial Asthma
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Luying XU, Ping LI, Huifen WU
Affiliations
  • Xiaoshan Hospital of Traditional Chinese Medicine,Hangzhou 311201,Zhejiang,China
Published: 2025-06-10 doi: 10.13193/j.issn.1673-7717.2025.06.041
Outline
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Objective

To investigate the effects of Xuanbai Chengqi Decoction(宣白承气汤)combined with budesonide formoterol inhalant on lung function and related inflammatory factors in children with rhinitis in remission of bronchial asthma.

Methods

A total of 188 children with asthma combined with rhinitis admitted to the hospital from January to December 2020 were divided into control group(94 cases,budesonide formoterol inhalant)and observation group(94 cases,Xuanbai Chengqi Decoction combined with budesonide formoterol inhalant)according to different treatment methods.The patients were treated for consecutive 8 weeks.The clinical efficacy(rale resolution time,cough resolution time and gasping relief time),lung function[lung capacity(FVC),forced expiratory volume at the end of the first second(FEV1),peak expiratory flow rate(PEF)]and inflammatory indicators[C-reactive protein(CRP),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)]of the two groups were observed and compared.Murray Lung injury score,acute physiological and chronic health score,serum leukotriene(LTD4),nerve growth factor(NGF)and TCM symptom and sign scores were compared.

Results

The time of rales disappearance,cough disappearance and gasping relief in the observation group were faster than those in the control group(P<0.05).After treatment,the levels of FVC,FEV1 and PEF in the observation group were significantly increased compared with those in the control group(P<0.05).After treatment,the levels of CRP,IL-6 and TNF-αin the observation group were significantly decreased compared with those in the control group(P<0.05).After treatment,Murray lung injury score and APACHEⅡscore of the two groups were lower than those before treatment,and the difference between the two groups was statistically significant(P<0.05).Compared with those before treatment,the levels of LTD4 and NGF in both groups were significantly decreased after treatment(P<0.05),and the levels of LTD4 and NGF in the observation group were significantly decreased(P<0.05).The scores of phlegm,nasal discharge,cold limbs,tongue quality and tongue coating in the observation group were significantly lower than those in control group(P<0.05).

Conclusion

Xuanbai Chengqi Decoction combined with budesonide formoterol inhalation has a significant effect in the treatment of children with bronchial asthma complicated with rhinitis,and can quickly relieve the clinical symptoms,improve the lung function,reduce the levels of inflammatory factors,Murray lung injury score and TCM symptom and sign scores.

children asthma  /  rhinitis  /  Xuanbai Chengqi Decoction(宣白承气汤)  /  budesonide  /  lung function  /  inflammatory factor
徐璐莹, 李萍, 吴慧芬. 宣白承气汤联合布地奈德福莫特罗吸入剂对支气管哮喘缓解期合并鼻炎患儿肺功能及相关炎症因子的影响. 中华中医药学刊, 2025 , 43 (6) : 200 -203 . DOI: 10.13193/j.issn.1673-7717.2025.06.041
Luying XU, Ping LI, Huifen WU. Effects of Xuanbai Chengqi Decoction(宣白承气汤)Combined with Budesonide Formoterol Inhalant on Lung Function and Related Inflammatory Factors in Children with Rhinitis in Remission of Bronchial Asthma[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (6) : 200 -203 . DOI: 10.13193/j.issn.1673-7717.2025.06.041
Year 2025 volume 43 Issue 6
25
9
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doi: 10.13193/j.issn.1673-7717.2025.06.041
  • Online Date:2026-10-30
  • Published:2025-06-10
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    Xiaoshan Hospital of Traditional Chinese Medicine,Hangzhou 311201,Zhejiang,China
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表12种不同金属材料的力学参数
科
Family
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Number of
genus
种数
Number of
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Percentage of
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Genus
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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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