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Research Progress on Chemical Composition and Pharmacological Effects of Lingzhi（Ganoderma）and Prediction Analysis of Quality Marker
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Jing RAN1, Zunbao YAO2, Hui XU1, Wei ZHANG1, Xueyuan BAI1
Chinese Archives of Traditional Chinese Medicine | 2025, 43(5) : 172 - 182
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Chinese Archives of Traditional Chinese Medicine | 2025, 43(5): 172-182
• Target on National Project •
Research Progress on Chemical Composition and Pharmacological Effects of Lingzhi（Ganoderma）and Prediction Analysis of Quality Marker
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Jing RAN1, Zunbao YAO2, Hui XU1, Wei ZHANG1, Xueyuan BAI1
Affiliations
  • 1.Changchun University of Chinese Medicine，Changchun 130021，Jilin，China
  • 2.Shenghe Family Farm of Xinglong Township，Fusong County，Baishan 134528，Jilin，China
Published: 2025-05-10 doi: 10.13193/j.issn.1673-7717.2025.05.032
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Lingzhi（Ganoderma）is the dried fruiting body of Zhenjun Chizhi［Ganoderma lucidum（Leyss.ex Fr.）Karst.］or Zizhi（Ganoderma sinense Zhao，Xu et Zhang）of the polyporeaceae fungus，which is a traditional Chinese precious medicinal material and is listed as the top grade. At present，the types of compounds isolated from Lingzhi（Ganoderma）mainly include polysaccharides，triterpenoids，proteins，sterols，vitamins and trace elements，etc.，which have a wide range of biological activities and pharmacological effects，such as regulating immunity，anti-cancer，anti-oxidation，anti-aging，anti-inflammatory，etc. In this paper，the chemical composition and pharmacological effects of Lingzhi（Ganoderma）were reviewed，and the quality markers（QMarker）were predicted from multiple aspects，and the polysaccharides of Lingzhi（Ganoderma），total triterpenoids of Lingzhi（Ganoderma），Ganoderic acid A，Ganoderic acid B，Ganoderic acid C2，Ganoderic acid E，Ganoderma lucidum kettotriol，Ganoderma lucidum terpene diol，ergosterol，ergosterol peroxide，Ganoderma lucidum uridine，uracil，protein，amino acids，trace elements，vitamin components and heavy metal elements（Pb，Cd，As，Hg）and other components may become Q-Markers of Lingzhi（Ganoderma），which provides a basis for the quality control and evaluation of Lingzhi（Ganoderma）.

Lingzhi（Ganoderma）  /  chemical composition  /  pharmacological action  /  quality evaluation  /  quality marker
冉靖, 姚遵宝, 徐慧, 张巍, 白雪媛. 灵芝化学成分、药理作用及质量标志物预测分析. 中华中医药学刊, 2025 , 43 (5) : 172 -182 . DOI: 10.13193/j.issn.1673-7717.2025.05.032
Jing RAN, Zunbao YAO, Hui XU, Wei ZHANG, Xueyuan BAI. Research Progress on Chemical Composition and Pharmacological Effects of Lingzhi（Ganoderma）and Prediction Analysis of Quality Marker[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (5) : 172 -182 . DOI: 10.13193/j.issn.1673-7717.2025.05.032
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Year 2025 volume 43 Issue 5
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doi: 10.13193/j.issn.1673-7717.2025.05.032
  • Online Date：2026-10-30
  • Published：2025-05-10
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    1.Changchun University of Chinese Medicine，Changchun 130021，Jilin，China
    2.Shenghe Family Farm of Xinglong Township，Fusong County，Baishan 134528，Jilin，China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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