To investigate the effects of Shengyu Decoction（圣愈汤）and Zengye Decoction（增液汤）combined with recombinant human granulocyte colony-stimulating factor on myelosuppression and peripheral blood image after chemotherapy for epithelial ovarian cancer.

All 75 patients were randomly divided into treatment group and control group according to the order of enrollment for epithelial ovarian cancer，35 cases in each group. The control group was prophylactically treated with pegylated recombinant human granulocyte colony stimulating factor（PEG-rhG-CSF）or recombinant human granulocyte colony stimulating factor（rhG-CSF）after chemotherapy. The treatment group was treated with Shengyu Decoction and Zengye decoction orally in addition to the treatment of the control group. The degree of myelosuppression after chemotherapy and peripheral blood images were observed at 1 day before chemotherapy，1，2 and 3 courses after chemotherapy.

The incidence of myelosuppression in the treatment group after 1，2 and 3 courses was significantly lower than that in the control group，and the difference was statistically significant（P<0.05）. There was no statistically significant difference in the levels of white blood cells，neutrophils，platelets or hemoglobin between the two groups before treatment（P>0.05）. The above indexes were both decreased after treatment and the decrease degree in the control group was significantly greater than that in the treatment group，and the difference was statistically significant（P<0.05）.

Shengyu Decoction and Zengye Decoction combined with recombinant human granulocyte colony-stimulating factor can reduce myelosuppression in patients with epithelial ovarian cancer，improve the decline of peripheral blood cells and promote the recovery of blood cell levels after chemotherapy.