Full
Outline
Dahuoluo Pills（大活络丸）originated from classic and famous recipes of the Ming dynasty of Wonderful Well-Tried Recipes，obtained after several increases and decreases，and were consisted of 48 kinds of herbs such as Mahuang（Ephedrae Herba），Qishe（Agkistrodon），Tiannanxing（Arisaematis Rhizoma），Shuiniujiao（Bubali Cornu）and so on. Tongren Dahuoluo Pills were added processed Fuzi（Aconiti Lateralis Radix Praeparata）and Fuling（Poria）. The dosage forms include honey pills，water pills，water honey pills，concentrated pills，etc. The whole prescription has the effects of dispelling wind，relaxing tendons，activating collateral and eliminating dampness，and could be used for the treatment of hemiplegia，rheumatic arthralgia，chest arthralgia and heartache. Through consulting and analyzing the relevant literature in recent years，the author has found that the Dahuoluo Pills have good effects of promoting blood circulation and removing blood stasis and neuroprotection，and could be used for osteoarthropathy（knee osteoarthritis，rheumatoid arthritis，lumbar disc herniation，osteonecrosis of femoral head），cerebrovascular diseases（cerebral apoplexy，insufficient blood supply），nerve injury（peripheral neuropathy，spinal cord injury），scapulohumeral periarthritis and so on. The quality control methods included spectrum detection，chromatography detection，multi-technology combination and so on，and were mainly based on high performance liquid chromatography and multi-technology combination. While the material basis and molecular mechanism still need to be improved. Here，the authors summarized and analyzed the findings about clinical applications，quality control and pharmacologic actions of Dahuoluo Pills，in order to provide more ideas and basis for their clinical application.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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