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Research Progress on Mechanism of Chinese Traditional Medicine Polysaccharide Regulating Immune Cells against Lung Cancer
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Chengzhi WANG1, Yifan LIU1, Xiaoqing ZHANG2, Gelei ZHAO1, Shan ZHANG1, Peimin LIU1, Dongdong LI1
Chinese Archives of Traditional Chinese Medicine | 2025, 43(4) : 149 - 154
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Chinese Archives of Traditional Chinese Medicine | 2025, 43(4): 149-154
• Target on National Project •
Research Progress on Mechanism of Chinese Traditional Medicine Polysaccharide Regulating Immune Cells against Lung Cancer
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Chengzhi WANG1, Yifan LIU1, Xiaoqing ZHANG2, Gelei ZHAO1, Shan ZHANG1, Peimin LIU1, Dongdong LI1
Affiliations
  • 1.The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450002, Henan, China
  • 2.The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China
Published: 2025-04-10 doi: 10.13193/j.issn.1673-7717.2025.04.024
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Lung cancer is one of the most common malignant tumors in the world,its morbidity and mortality rank first,and has become the number one killer threatening human life and health in the world. Traditional Chinese medicine is widely used in the comprehensive treatment of anti-lung cancer,and its curative effect is exact. As the most common active component of traditional Chinese medicine,traditional Chinese medicine polysaccharide has a prominent anti-tumor immune effect. A large number of studies have found that traditional Chinese medicine polysaccharides,such as Astragalus polysaccharides,Ginseng polysaccharide,Epimedium polysaccharides,Ganoderma lucidum polysaccharide,Achyranthes bidentata polysaccharides and Dendrobium polysaccharide,can improve the immune microenvironment of lung cancer tumors by regulating immune cells such as macrophages,dendritic cells,natural killer cells,myeloid suppressor cells,T cells and regulatory T cells to improve the function and activity of immune cells and enhance the body's immune response,so as to better play the role of anti-lung cancer. By collecting literatures on the anti-lung cancer effect of traditional Chinese medicine polysaccharides at home and abroad in recent years,this paper discussed the regulation of immune cells by traditional Chinese medicine polysaccharides and the specific mechanism of its anti-lung cancer effect,with a view to providing new ideas for the anti-lung cancer treatment of TCM as well as a new theoretical basis for the research and development of clinically related new drugs,and promoting the extensive clinical application of integrated traditional Chinese and western medicine in the treatment of lung cancer.

polysaccharide  /  immune cells  /  lung cancer  /  mechanism study
王成志, 刘一帆, 张晓青, 赵戈蕾, 张山, 刘培民, 李东东. 中药多糖调节免疫细胞抗肺癌作用机制研究进展. 中华中医药学刊, 2025 , 43 (4) : 149 -154 . DOI: 10.13193/j.issn.1673-7717.2025.04.024
Chengzhi WANG, Yifan LIU, Xiaoqing ZHANG, Gelei ZHAO, Shan ZHANG, Peimin LIU, Dongdong LI. Research Progress on Mechanism of Chinese Traditional Medicine Polysaccharide Regulating Immune Cells against Lung Cancer[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (4) : 149 -154 . DOI: 10.13193/j.issn.1673-7717.2025.04.024
Year 2025 volume 43 Issue 4
54
24
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doi: 10.13193/j.issn.1673-7717.2025.04.024
  • Online Date:2026-10-30
  • Published:2025-04-10
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    1.The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450002, Henan, China
    2.The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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