收藏切换
Research Progress of Ferroptosis Related LncRNA in Prevention and Treatment of Cerebral Ischemia-Reperfusion Injury by Traditional Chinese Medicine
收藏切换
Chengcheng FAN, Xinyu ZHANG, Ao WANG, Shengpeng WANG, Mengyue SUN, Zhe WANG, Jidong LIU
Chinese Archives of Traditional Chinese Medicine | 2025, 43(4) : 52 - 58
Less
收藏切换
Chinese Archives of Traditional Chinese Medicine | 2025, 43(4): 52-58
• Target on National Project •
Research Progress of Ferroptosis Related LncRNA in Prevention and Treatment of Cerebral Ischemia-Reperfusion Injury by Traditional Chinese Medicine
Full
Chengcheng FAN, Xinyu ZHANG, Ao WANG, Shengpeng WANG, Mengyue SUN, Zhe WANG, Jidong LIU
Affiliations
  • Liaoning University of Traditional Chinese Medicine, Shenyang 110847, Liaoning, China
Published: 2025-04-10 doi: 10.13193/j.issn.1673-7717.2025.04.010
Outline
收藏切换

Ferroptosis,a pattern of cell apoptosis driven by iron-dependent lipid peroxidation,plays an important role in the complex pathological process of cerebral ischemia-reperfusion injury. This type of injury usually occurs during the recovery of blood flowing after cerebral ischemia,when the brain tissue undergoes a more severe secondary injury. In a series of complex physiological reactions,multiple mechanisms such as oxidative stress,excessive intracellular calcium concentration and inflammation work together,ferroptosis is a part of them which cannot be ignored. Recent studies have shown that certain LncRNAs can significantly affect the process of cerebral ischemia-reperfusion injury by influencing the expressions of ferroptosis-related genes. Some LncRNAs play a role in the process of apoptosis after cerebral ischemia-reperfusion injury by regulating the expression of genes related to autophagy. The research on how LncRNA affects ferroptosis in cerebral ischemia-reperfusion injury is still in its initial stage,but the research value and application potential in this field have already emerged. In the future,we can further explore the mechanisms by which LncRNAs regulate ferroptosis and strive to discover more LncRNAs related to ferroptosis,in order to find new methods and ways for treating cerebral ischemia-reperfusion injury.

ischemic stroke  /  cerebral ischemia-reperfusion injury  /  stroke  /  ferroptosis  /  LncRNA  /  therapy of traditional Chinese medicine
樊程程, 张新宇, 王奡, 王圣澎, 孙梦月, 王哲, 刘继东. 铁死亡相关LncRNA在中医药防治脑缺血再灌注损伤中的研究进展. 中华中医药学刊, 2025 , 43 (4) : 52 -58 . DOI: 10.13193/j.issn.1673-7717.2025.04.010
Chengcheng FAN, Xinyu ZHANG, Ao WANG, Shengpeng WANG, Mengyue SUN, Zhe WANG, Jidong LIU. Research Progress of Ferroptosis Related LncRNA in Prevention and Treatment of Cerebral Ischemia-Reperfusion Injury by Traditional Chinese Medicine[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (4) : 52 -58 . DOI: 10.13193/j.issn.1673-7717.2025.04.010
Year 2025 volume 43 Issue 4
49
19
Cite this Article
BibTeX
Article Info
doi: 10.13193/j.issn.1673-7717.2025.04.010
  • Online Date:2026-10-30
  • Published:2025-04-10
Article Data
Affiliations
History
Funding
Affiliations
    Liaoning University of Traditional Chinese Medicine, Shenyang 110847, Liaoning, China
References
Share
https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/10.13193/j.issn.1673-7717.2025.04.010
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT