To observe the effect of Modified Zuogui Pill（左归丸加减）combined with moxibustion in the treatment of kidney Yin deficiency type of diminished ovarian reserve，and to explore whether moxibustion combined with medicine can improve the therapeutic effect of kidney Yin deficiency type of diminished ovarian reserve.

A total of 60 patients meeting the diagnostic criteria for kidney Yin deficiency type of diminished ovarian reserve in the gynecological outpatient department of Huaibei Hospital of Traditional Chinese Medicine of Anhui Province from January 2022 to December 2022 were collected as research subjects，and were randomly divided into treatment group and control group，with 30 patients in each group. The control group received moxibustion treatment，and the treatment group received Modified Zuogui Pill and moxibustion treatment. Both groups were treated for 3 consecutive menstrual cycles. The levels of serum estradiol（E2），follicle-stimulating hormone（FSH）and luteinizing hormone（LH）of the two groups were measured before and after treatment. Basal sinus follicle count and endometrial thickness were monitored before and after treatment，and TCM syndrome scores of the two groups were recorded before and after treatment.

The total effective rate of the treatment group and the control group was 93.33% and 73.33%，respectively（P<0.05）. After treatment，the level of E2，endometrial thickness and sinus follicle count in the treatment group were higher than those in the control group，and the levels of FSH，LH and the scores of small abdominal pain during menstruation，delayed menstruation and dark color or purple were lower than those in the control group（P<0.05）.

Zuogui Pill combined with moxibustion has significant curative effect in the treatment of kidney Yin deficiency type of diminished ovarian reserve，symptoms and hormone levels are significantly improved，which is suitable for popularization and application.