Full
Outline
To establish the TCM syndrome differentiation model of cancer pain based on artificial intelligence，so as to provide basis for the development of TCM syndrome differentiation of cancer pain.
The TCM medical record data of cancer pain was collected from CNKI，VIPChinese Science and Technology periodical Database，Wanfang database，China Biology Medicine disc，and Ancient and Modern Medical Record Cloud Platform from the embellishment time up to September 2023. Machine learning algorithms，such as linear support vector classification（LSVC），nearest centroid（NC），multinomial Na？ve Bayes（MNB），random forest（RF），stochastic gradient descent（SGD）and multilayer perceptron（MLP）were used to quantitatively analyze the data set，and the syndrome differentiation model of cancer pain was established. The model was evaluated by 5-fold cross validation. The evaluation indexes included Accuracy，Precision，Recall，F1 score and AUC value.
There were 72 input variables and 6 output variables for TCM syndromes of cancer pain. The Accuracy，Precision，Recall and F1 score of the six models were all above 0.89，and the AUCvalue was above 0.94. Among them，the Accuracy，Precision and Recall of the nearest centroid model were the highest. The Accuracy，precision，recall and F1 score were 0.978，0.980，0.978 and 0.977，respectively，and the AUCvalue was 0.986，which was higher than other algorithm models. The TCM interpretation of the parameters basically accorded with the principle of TCM diagnosis.
The TCM syndrome differentiation model of cancer pain based on the nearest centroid algorithm model has high diagnosis and prediction ability，which can provide reference for clinical workers to carry out TCM intelligent syndrome differentiation of cancer pain.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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