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Effects of Chaihu Qingshang Decoction(柴胡清上汤)Combined with Gaze Stability Vestibular Rehabilitation Training on Vestibular Function and Oxidative Stress in Patients with Vestibular Neuritis
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Deping LI, Zhiguo MIAO, Zhen LI, Xiaoqiang GONG, Bo LIU
Chinese Archives of Traditional Chinese Medicine | 2025, 43(1) : 226 - 230
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Chinese Archives of Traditional Chinese Medicine | 2025, 43(1): 226-230
• Platform of Provincial Project •
Effects of Chaihu Qingshang Decoction(柴胡清上汤)Combined with Gaze Stability Vestibular Rehabilitation Training on Vestibular Function and Oxidative Stress in Patients with Vestibular Neuritis
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Deping LI, Zhiguo MIAO, Zhen LI, Xiaoqiang GONG, Bo LIU
Affiliations
  • Zhengzhou Traditional Chinese Medicine Hospital, Zhengzhou 450007, Henan, China
Published: 2025-01-10 doi: 10.13193/j.issn.1673-7717.2025.01.041
Outline
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Objective

To explore the effectof Chaihu Qingshang Decoction(柴胡清上汤)combined with gaze stability vestibular rehabilitation training on vestibular function and oxidative stress in patients with vestibular neuritis.

Methods

Sixty patients with vestibular neuritis who were diagnosed in the hospital from July 2021 to December 2022 were selected as research objects,and were randomly divided into the experimentgroup and the control group,with 30 patients in each group. The control group was given routine and symptomatic treatment,and the experiment group was given Chaihu Qingshang Decoction combined with gaze stability vestibular rehabilitation training on the basis of the control group. The clinical efficacy,dizziness symptom assessment scale,dizziness disorder scale,specific activity balance confidence scale,vestibular function,serum inflammatory factors,oxidative stress indicators and incidence of adverse reactions were compared between the two groups before and after treatment.

Result

After treatment,compared with the total effective rate(63.33%,19/30)in the control group,the total effective rate(86.67%,26/30)in the experimental group was higher(P<0.05). Compared with those before treatment,the Vertigo Symptom Rating Scale(DARS)and Dizziness Handicap Inventory(DHI)scores of both groups were significantly reduced,while the activities-specific balance confidence scale(ABC)scores were increased(P<0.05). After treatment,compared with the control group,the experimental group had lower DARSand DHIscores,and higher ABC scores(P<0.05). Compared with that before treatment,semicircular canal paresis(CP)value,scanning wave amplitude,spontaneous nystagmus intensity and shaking head nystagmus intensity of semicircular canals paresis patients in the two groups decreased significantly,and semicircular canals gain increased significantly(P<0.05). After treatment,compared with those of the control group,the CP value,scanningwave amplitude,spontaneous nystagmus intensity and shaking head nystagmus intensity of semicircular canals paresis in the experiment group were lower,and the semicircular canals gain was higher(P<0.05). Compared with those before treatment,the serum levels of IL-6 and TNF-αin both groups significantly decreased(P<0.05). And compared with those of the control group,the levels of the experimental group were relatively low(P<0.05). Compared with those before treatment,the levels of SOD in both groups significantly increased,while the levels of MDA decreased(P<0.05). Compared with the control group,the experimental group had higher level of SOD and lower level of MDA(P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).

Conclusion

Chaihu Qingshang Decoction combined with gaze stability vestibular rehabilitation training can effectively improve the overall therapeutic effect of patients with vestibular neuritis,regulate inflammation and oxidative stress in the body,significantly improve vestibular function,alleviate nystagmus and semicircular canals paresis,which is suitable for clinical promotion.

Chaihu Qingshang Decoction(柴胡清上汤)  /  gazing stability vestibular rehabilitation training  /  vestibular neuritis  /  vestibular function  /  oxidative stress
李得平, 苗治国, 李振, 龚晓强, 刘博. 柴胡清上汤联合凝视稳定性前庭康复训练对前庭神经炎前庭功能和氧化应激的影响. 中华中医药学刊, 2025 , 43 (1) : 226 -230 . DOI: 10.13193/j.issn.1673-7717.2025.01.041
Deping LI, Zhiguo MIAO, Zhen LI, Xiaoqiang GONG, Bo LIU. Effects of Chaihu Qingshang Decoction(柴胡清上汤)Combined with Gaze Stability Vestibular Rehabilitation Training on Vestibular Function and Oxidative Stress in Patients with Vestibular Neuritis[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (1) : 226 -230 . DOI: 10.13193/j.issn.1673-7717.2025.01.041
Year 2025 volume 43 Issue 1
33
14
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doi: 10.13193/j.issn.1673-7717.2025.01.041
  • Online Date:2026-10-30
  • Published:2025-01-10
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    Zhengzhou Traditional Chinese Medicine Hospital, Zhengzhou 450007, Henan, China
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表12种不同金属材料的力学参数
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Family
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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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