To analyze the effectof Xuefu Zhuyu Decoction（血府逐瘀汤）on lipoprotein-associated phospholipase A2（Lp-PLA2），monocyte chemoattractant protein-1（MCP-1），soluble intercellular adhesion molecule-1（sICAM-1），inflammatory factors and quality of life in patients with coronary heart disease unstable angina pectoris with phlegm turbidity and obstruction type.

A total of 120 patients with coronary heart disease unstable angina pectoris with phlegm turbidity and obstruction were included，and they were randomly divided into observation group and control group，60 cases in each group. The patients in the control group were treated with conventional western medicine，and the observation group was given Modified Xuefu Zhuyu Decoction on this basis，and the treatment period of both groups was 8 weeks. After the treatment，the clinical curative effect，angina pectoris attack，TCM clinical symptom scores，inflammatory factor levels，Lp-PLA2，MCP-1，sICAM-1 and quality of life were observed in the two groups.

After treatment，the total effective rate of the observation group was 90.00%（54/60），which was significantly higher than that of the control group（P<0.05）. At the same time，the frequency of angina pectoris attack，duration and pain degree of the observation group were more significantly improved than those of the control group（P<0.05）. The changes of TCM clinical symptom scores of body fatigue，excessive phlegm and anorexia were significantly improved compared with those before treatment（P<0.05）and the improvement of each symptom score in the observation group was significantly better than that in the control group（P<0.05）. The levels of interleukin-4（IL-4），interleukin-6（IL-6），interleukin-8（IL-8）and tumor necrosis factor-α（TNF-α）of the two groups after treatment decreased compared with those before treatment（P<0.05）and the decrease in the observation group was better than that of the control group. The levels of Lp-PLA2，MCP-1 and sLCAM in the two groups after treatment were significantly lower than those before treatment（P<0.05），and the improvement in the observation group was significantly better than that in the control group（P<0.05）. After treatment，the MOS item short from health survey（SF-36）scores of the two groups were both significantly improved compared with those before treatment（P<0.05），and the quality of life in the observation group was significantly better than that in the control group.

Xuefu Zhuyu Decoction can effectively improve the clinical treatment effect of patients with coronary heart disease unstable angina pectoris with phlegm turbidity and obstruction type，reduce the frequency and degree of angina pectoris，improve the clinical symptoms of patients，increase the levels of inflammatory factors，reduce the levels of Lp-PLA2，MCP-1 and sICAM-1 and improve the quality of life of patients.