Full
Outline
Chuanxinlian（Andrographis paniculata）has become a commonly used medicinal plant in China，with the efficacy of clearing heatand removing toxins，cooling blood，eliminating swelling and drying dampness，playing a pivotal role in clinical application. Its chemical compositionmainly includes lactones，flavonoids，phenylpropanoids and other components，with antipyretic，antibacterial，antiviral，antitumor，regulating immunity，improving the cardiovascular system and other pharmacological effects，and is commonly used in the clinic for the treatment of a variety of infectious diseases，tumors as well as thrombotic occlusive vasculitis and so on. The article summarized the chemical composition and pharmacological effects of Chuanxinlian（Andrographis paniculata）in a systematic and comprehensive way，and based on this，it introduced the concept of “quality markers” in traditional Chinese medicine，and carried out the prediction and analysis of the quality markers of Chuanxinlian（Andrographis paniculata）from the aspects of phytopharmacology and chemical composition uniqueness，chemical composition and traditional medicinal properties，chemical composition and traditional efficacy，chemical composition measurability，different compounding environments，and transmission and traceability of chemical compositions. The results revealed that diterpene lactone，flavonoids and alkaloids can be used as candidate species of the quality markers of Chuanxinlian（Andrographis paniculata）. It was initially hypothesized that andrographolide，deoxyandrographolide，dehydroandrographolide，neoandrographolide，panicoin，luteolin and apigenin can be used as candidate compounds of the quality markers of Chuanxinlian（Andrographis paniculata），which can lay the foundation of the establishment of the perfect quality evaluation system of Chuanxinlian（Andrographis paniculata）aswell as provide guidance to guarantee the quality of Chuanxinlian（Andrographis paniculata）in the hope of letting the chemical and pharmacological researches serve better to the clinic.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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