Full
Outline
Wumei Pill（乌梅丸）is recorded in Treatise on Cold Damage and Miscellaneous Diseases which is a traditional Chinese medicine classic during the Eastern Han Dynasty in China. It is said that“for those who suffer from roundworms and convulsions，Wumei Pill is the main treat mentmethod. It also can treat long-term diarrhea.”This formula is composed of 10 Chinese herbal medicines，including Wumei（Mume Fructus），Xixin（Asari Herba），Guizhi（Cinnamomi Ramulus），Huanglian（Coptidis Rhizoma），Huangbai（Phellodendri Cortex），Danggui（Angelicae Sinensis Radix），Ganjiang（Zingiberis Rhizoma），Fuzi（Aconiti Lateralis Preparata Radix），Renshen（Ginseng Radix）and Shujiao（Zanthoxyli Pericarpium）. Itsmain efficacy is to warm liver and regulate themiddle，clear the upper and warm the lower parts. In clinical research，its modified formulae or combination with Western medicine are often used to treat multiple digestive system diseases such as ulcerative colitis，irritable bowel syndrome，chronic atrophic gastritis，gastroesophageal reflux disease，gastric cancer and intestinal polyps. Modern pharmacology shows that Wumei Pill plays important pharmacological roles in the treatment of gastrointestinal diseases，including anti-inflammatory，antioxidant，gastricmucosal protection，anti-tumor and antiulcer effects. This article used literature reports to summarize and generalize the effective ingredients of the formula from three aspects：clinical reports，pharmacological research on digestive system diseases and animal experiment reports. Based on the effective ingredients of the formula in relevant reports，the main effective ingredients of the formula used in common digestive system diseases were summarized，and the compatibility rules of the formula were explained through its pharmacological ingredients，in order to provide reference for the clinical application and related research of Wumei Pill.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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