Nephrotic syndrome（NS）is a common clinical syndrome in kidney diseases，characterized by high levels of proteinuria，hyperlipidemia，edema and hypoproteinemia. Primary nephrotic syndrome（PNS）is more common in children. The unclear pathogenesis of NS，hormone dependence in children，repeated urinary protein，hormone insensitivity and the possibility of some children progressing to end-stage kidney disease are still urgent clinical problems to be solved. Therefore，scientific and standardized individualized treatment plans are crucial for NS patients. In recent years，relevant domestic and foreign institutions have developed a series of guidelines and consensus for NS，clarifying the diagnosis，treatment and other related content. The understanding of the disease continues to deepen，but there are controversies in some aspects. Therefore，it is still necessary to continue to explore more flexible treatment plans and find out the optimal treatment. The article analyzed and compared the relevant guidelines and consensus treatment plans for nephrotic syndrome both domestically and internationally，in order to understand the latest progress in the treatment of NS with traditional Chinese and Western medicine，explore more flexible and practical individualized treatment plans，clarify further research directions and provide reference for clinical diagnosis and treatment as well as the formulation of related guidelines in the later stage.