Full
Outline
Lumbar degenerative disc disease（LDDD）and sarcopenia are common age-related motor system diseases in the elderly，which seriously affect the health of the elderly. The reduction of paravertebral muscle is the manifestation of sarcopenia in the spine，and clinical findings show the paravertebral sarcopenia and LDDD often present comorbidity status，mutual influence and mutual causality. Basic research suggests that the two have similar pathogenesis and pathological mechanisms. LDDD is mostly treated symptomatically in clinical practice，and there is still a lack of effective means to reverse in tervertebral disc degeneration. The common intervention methods for sarcopenia include resistance exercise and nutritional supplementation，but there is a lack of effective therapeutic drugs. Traditional Chinese medicine（TCM）classifies LDDD as “lumbago” and “spinalgia” and paravertebral sarcopenia as “Wei syndrome” and “consumptive disease”. TCM has a profound understanding of the relationship between the two，and highly summarizes the pathological state of its comorbidity with the theory of “bone and flesh notmatch”. It is believed that the deficiency of spleen and kidney is the common pathogenesis. Tonifying spleen and kidney is the basic treatment method. However，the research on traditional Chinese medicine urgently needs to adopt real-world research to enrich theories and evidence-based medicine research to verify therapeutic effects and basic experimental research to deeply reveal the mechanisms of comorbidities and explain the mechanisms of therapeutic effects，providing new ideas for deepening the relevant theories of traditional Chinese medicine and inventing new drugs.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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