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Mechanism and Treatment of IgA Nephropathy Based on“Interior-Exterior Relationship between Lung and Large Intestine”
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Yanyue ZHANG1, 2, 3, 4, Xuming ZHANG1, 2, 3, 4, Jiabao ZHOU1, 2, 3, 4, Feng YANG1, 2, 3, 4, Zhiyuan WU1, 2, 3, 4, Jiandong GAO1, 2, 3, 4
Chinese Archives of Traditional Chinese Medicine | 2025, 43(1) : 77 - 80
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Chinese Archives of Traditional Chinese Medicine | 2025, 43(1): 77-80
• Target on National Project •
Mechanism and Treatment of IgA Nephropathy Based on“Interior-Exterior Relationship between Lung and Large Intestine”
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Yanyue ZHANG1, 2, 3, 4, Xuming ZHANG1, 2, 3, 4, Jiabao ZHOU1, 2, 3, 4, Feng YANG1, 2, 3, 4, Zhiyuan WU1, 2, 3, 4, Jiandong GAO1, 2, 3, 4
Affiliations
  • 1.Department of Nephrology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • 2.Nephropathy Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • 3.Shanghai Key Laboratory of Traditional Chinese Clinical Medicine, Shanghai 201203, China
  • 4.Ministry of Education, Key Laboratory of Liver and Kidney Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
Published: 2025-01-10 doi: 10.13193/j.issn.1673-7717.2025.01.015
Outline
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IgA nephropathy（IgAN）is the most common primary glomerular disease world wide and a common cause of endstage renal disease. At present，it is difficult to explain the etiology and pathogenesis. With the deepening of research，many scholars have found that intestinal flora dysbiosis and mucosal immune response are closely related to the occurrence and development of this disease. The clinical progression of IgAnephropathy caused and exacerbated by respiratory infections cannot be ignored. This article attempted to summarize and analyze the relationship among lung，intestines and IgAN based on the classic traditional Chinese medicine theory of “interior-exterior relationship between lung and large intestine” combined with modern medical research，in order to consider the possible prevention and treatment mechanisms of drugs applied to IgAN based on the theory of “interior-exterior relationship between lung and large intestine” and provide new directions for the clinical treatment and research of IgAN.

interior-exterior relationship between lung and large Intestine  /  IgA nephropathy  /  intestinal flora  /  mucosal immunity
张艳玥, 张栩铭, 周嘉宝, 杨枫, 吴志远, 高建东. 基于“肺与大肠相表里”探讨IgA肾病的机制与治疗. 中华中医药学刊, 2025 , 43 (1) : 77 -80 . DOI: 10.13193/j.issn.1673-7717.2025.01.015
Yanyue ZHANG, Xuming ZHANG, Jiabao ZHOU, Feng YANG, Zhiyuan WU, Jiandong GAO. Mechanism and Treatment of IgA Nephropathy Based on“Interior-Exterior Relationship between Lung and Large Intestine”[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (1) : 77 -80 . DOI: 10.13193/j.issn.1673-7717.2025.01.015
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Year 2025 volume 43 Issue 1
38
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Article Info
doi: 10.13193/j.issn.1673-7717.2025.01.015
  • Online Date：2026-10-30
  • Published：2025-01-10
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Affiliations
    1.Department of Nephrology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    2.Nephropathy Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    3.Shanghai Key Laboratory of Traditional Chinese Clinical Medicine, Shanghai 201203, China
    4.Ministry of Education, Key Laboratory of Liver and Kidney Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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