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To explore the relationship between the prevalence of arthritis and cognitive function in the elderly and to verify the mediating effect of activities of daily living(ADL) and the moderating effect of social engagement to provide a reference point for promoting active aging.
This study based on the data of China Health and Retirement Longitudinal Study (CHARLS) in 2020, a moderated mediated-effects model was constructed using the PROCESS 4.1 program to analyze the mechanisms of ADL and social engagement in the effects of arthritis on cognitive function in the elderly.
A total of 5 882 elderly were enrolled in this study. The prevalence of arthritis in the elderly had a significant negative effect on cognitive function (β=-1.050, P<0.001); ADL partially mediated between the two, with a significant mediating effect (95% CI:-0.430--0.194), and an effect value of -0.306, with an effect percentage of 29.1%; social engagement significantly moderated the effect of ADL on cognitive function (β=1.594, P<0.001), and the predictive effect of ADL on cognitive function was more significant for the elderly with low social engagement.
ADL mediates the relationship between arthritis prevalence and cognitive function in the elderly; social engagement moderates the relationship between ADL and cognitive function; the elderly should be more aware of precautions to reduce the incidence of the disease; family doctor service teams should strengthen the health management and early intervention of arthritis in the elderly and provide scientific guidance on the use of medication; enhance the ADL of the elderly; and encourage the social engagement of the elderly to strengthen their cognitive function and achieve active ageing.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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