Based on the person-environment fit (PEF) theory, a theoretical model of worker-occupation fit related stress (MWOFS) is constructed to provide theoretical support and practical guidance for the identification and intervention of occupational stress.

Integrating theoretical analysis with empirical validation, the MWOFS model was constructed through literature comparison, inductive reasoning, and programmatic decision-making methods. A logistic regression model was used to examine the interaction effect between worker occupation fit and occupational stress on psychological, physical, and social outcomes. Furthermore, the impact of poor fit on the risk of health outcomes was calculated.

The conceptual model of the MWOFS was established based on the core elements of worker occupation fit, occupational stress, and stress related disorders. The content model provided theoretical guidance for empirical research by expanding the core elements and formulating pathway hypotheses for validation. This study included a total of 3 451 healthcare-related workers as research subjects. The empirical results showed that the interaction between misfit and occupational stress increased the risk of stress-related disorders. Compared to individuals with worker occupation fit, those with misfit exhibited elevated risks for mental responses (34.7%), physiological responses (23.1%), and chronic diseases (10.9%).

MWOFS provides a reasonable framework for integrating influencing factors of occupational stress. It also scientifically evaluates the principal health impairments in working populations arising from the interaction between workeroccupation fit and occupational stress, and proposes innovative approaches for risk stratified management of occupation related diseases and the development of targeted intervention strategies.