Objective To optimize the detection ability of Staphylococcus aureus in our laboratory by participating in the verification of the detection ability of Staphylococcus aureus in cosmetics organized by the Test and Evaluation Center of Chinese Academy of Inspection and Quarantine. Methods The samples were tested according to the test instructions of ACAS-PT1637 (2023) for the detection ability of Staphylococcus aureus in cosmetics and the Technical Specification for Cosmetic Safety (2015 edition). At the same time, the conventional biochemical detection methods, ATB bacteria identification and fluorescence quantitative PCR amplification were used to detect. Results Staphylococcus aureus was not detected in sample 23-Q777 and Staphylococcus aureus was detected in sample 23-A973. The result of this ability verification is satisfactory. Conclusion By participating in this capability verification, the laboratory not only improved the detection ability of the bacteria, but also effectively demonstrated that the laboratory has the ability to detect Staphylococcus aureus in cosmetics by using a variety of methods.

Inter-cresol is a common environmental pollutant and industrial raw material, and its sensitive, accurate and rapid detection is crucial for environmental monitoring and food safety. Molecularly imprinted polymers (Molecularly Imprinted Polymers, MIPs) have shown an attractive application prospect in improving the detection method due to their unique molecular recognition ability. This paper systematically discusses the application of MIPs technology in improving detection sensitivity, simplifying sample processing and enhancing selective identification, and puts forward a series of innovative imprinting strategies and detection schemes, in order to provide new ideas and methods for solving the current technical bottleneck in parcresol detection.

Objective To study, discuss and analyze the reasons for deviations in drug test results and find out methods for quality control. Methods 150 drug samples from October 2022 to October 2023 were randomly collected and tested using two methods: UV spectrophotometry and high performance liquid chromatography. The results of the drug samples tested by the two methods were comparatively analyzed. Find out the reasons for deviations in drug test results, and finally conduct further research based on the situation of the drugs to find ways to control drug quality. Results The deviation rate of the drug detected by UV spectrophotometry was 4%, and the deviation rate of the test results obtained by high-performance liquid chromatography was 3.33%. The difference between the groups was not statistically significant (P>0.05). The two methods were used to detect the deviation rate. The deviation rate of drug test results is different, but the difference is not significant. Conclusion There are many factors that cause deviations in drug testing results. To ensure that drug testing results have high accuracy, scientific and reasonable testing methods and technologies must be used to ensure the standardization of operations during testing and reduce the impact of variable factors on The influence of test results can reduce errors, improve the accuracy of test results, maximize the efficacy of drugs, and ensure the quality of drugs.

Drug testing is a professional work, which contains many details, any link will affect the efficiency and quality of the overall work. High performance liquid chromatography (HPLC) has the characteristics of high sensitivity, short test time and wide application range. Its application in drug testing can improve the shortcomings of traditional testing techniques and make the test results more reliable and accurate. This paper first describes the concept of high performance liquid chromatography, then analyzes the characteristics of high performance liquid chromatography, including short detection time, high sensitivity and wide application range, and then analyzes the value of practicing high performance liquid chromatography in drug testing, including timely detection of drug processing problems, ensuring drug safety, and promoting the improvement of drug testing technology. Finally, the application of high performance liquid chromatography in drug testing was discussed.

Objective To systematically control the quality of nucleic acid testing laboratories through the HACCP system, in order to improve the quality of nucleic acid testing laboratories and provide reference for effectively formulating quality control strategies for nucleic acid testing. Methods Preliminary exploration of quality control in nucleic acid testing laboratories based on the HACCP system, with a focus on analyzing the monitoring procedures, validation measures, and corrective measures developed by the HACCP system in the stages of nucleic acid sample reception, preparation of reagents, sample nucleic acid extraction, nucleic acid amplification, result interpretation, and nucleic acid testing result reporting. Results By analyzing the testing data December 2021 to December 2022, the results showed that all batches of nucleic acid positive quality control products met the judgment rules, and each batch of experiments was in a controlled state. Statistical analysis was conducted on laboratory data under the HACCP system, calculating their standard deviation, mean, and coefficient of variation. After plotting the box plot, outlier tests were conducted, and it was found that the mean did not produce outliers. Conclusion The application of HACCP system in nucleic acid testing laboratories can effectively control the quality of nucleic acid testing laboratories, comprehensively control important control points of nucleic acid testing laboratories, improve the level and quality of laboratory biosafety,

Since the safety of medical university laboratories is affected by many factors and shows a trend of increasing installation hazards, this paper establishes a medical university laboratory safety evaluation system based on hierarchical analysis-fuzzy comprehensive evaluation method by combining the results of various scholars on the research of laboratory safety evaluation system in colleges and universities. And through the evaluation system of a college laboratory safety evaluation to the evaluation of the scientific analysis, the results show that through the evaluation system can get more objective safety evaluation results.

Objective Reasonably set up and implement the measurement and calibration scheme of the yoke magnetic particle flaw detector, including calibration demand analysis, calibration preparation, calibration implementation, calibration work after calibration, calibration summary and analysis, etc., to improve the lifting force, safety, permeability and sensitivity of the yoke magnetic particle flaw detector. Methods Taking the CDX-III magnetic yoke magnetic particle flaw detection machine as an example, the calibration implementation preparation, working environment simulation, power inspection, insulation resistance and strength test, current error test, current measuring device access, sensitivity detection and other specific schemes were reasonably designed. Experimental research method was adopted to analyze the rationality of the calibration scheme through experimental results. Results Through the use of this measurement calibration scheme, the lifting force, safety, permeability and sensitivity of the yoke magnetic particle flaw detection machine can be improved to meet the national metrology standards and requirements. Conclusion This measurement calibration scheme has systematic and fine characteristics, and pays attention to the use of environmental simulation, enhance its practicality and rationality, more comprehensive and accurate, worthy of promotion and use.

Based on the primary inspecting and testing institutions, combined with the actual work, this paper discusses some common problems such as the development position, encouragement and incentive mechanism, talent team construction, scientific and technological innovation, scientific and technological achievements transformation of the current market supervision system from the aspects of quality infrastructure construction, scientific and technological innovation, and a number of suggestions are given.

Large instruments and equipment provide an important material foundation for teaching, research and talent cultivation in universities. Promoting the open sharing of large instruments and equipment and improving the efficiency of instrument use is the focus of large instrument and equipment management. The paper combines the practice of Central South University to build an open sharing mechanism, including the construction of university-level public platform to promote centralized and intensive management; optimize the shared service platform to promote the transformation of service mode; strengthen the assessment and evaluation of instruments, focusing on the use of assessment results; strengthen the construction of talent team to mobilize the enthusiasm of experimental personnel.

Objective This paper focuses on the collaborative optimization of on-site detection technology and quality control systems in occupational hygiene. Methods By comprehensively analyzing traditional and modern detection methods, as well as the construction and management of quality control systems, the paper reveals the technological challenges and trends in the modern industrial environment. Results Strategies such as the application of advanced detection technology in quality control, optimization of data integration and analysis, construction of intelligent decision support systems, and the design of collaborative workflows are proposed to comprehensively enhance the efficiency of occupational hygiene detection. Conclusion The research of this paper provides robust support for the technological development and quality control practices in the field of occupational hygiene.