In order to steadily enhance the laboratory certification and accreditation capabilities, to achieve accurate input, scientific disposal and efficient sharing of complex test data information, to meet the requirements of diversified use. On the basis of mastering the positioning of measurement information management system, this paper focuses on the main contents of laboratory certification and accreditation, improves the system application process, improves the system application path, details the main points of system application, and continuously improves the laboratory operation efficiency.

Objective: This study aims to explore a method for determining the concentration of free amino acids in cell culture media based on ultra performance liquid chromatography (UPLC). Methods Researchers used UPLC technology combined with optimized sample processing Methods to efficiently and accurately determine free amino acids in cell culture medium. Results The research results indicate that the UPLC method can quickly and reliably determine the concentration of free amino acids in cell culture medium, providing an effective means for monitoring and optimizing cell culture in the biopharmaceutical industry. Conclusion Accurate determination of amino acid concentration not only helps to better understand the dynamic changes of key nutrients in cell culture media, but also provides important data support for process optimization in the production process.

Objective To analyze the microbiological testing results of hotels, bathing centers, and supermarkets. Methods According to the requirements of the Technical Specification for Public Place Hygiene Monitoring and the Public Place Hygiene Standard Monitoring and Inspection Method, a total of 2372 samples from three types of public places (hotels, bathing centers, supermarkets) were subjected to microbiological testing. Results After analyzing the microbiological testing results of air and public goods from 2021 to 2022, a total of 1124 samples were tested in 2021, of which 1110 were qualified, with a qualification rate of 98.75%; In 2022, a total of 1248 samples were tested, of which 1248 were qualified, with a qualification rate of 100.00%. The microbiological testing results of air and public goods in 2022 were higher than those in 2021 (x2 value=13.586, P<0.05). Conclusion The qualified rate of microbial testing in public places in Jiangyin City in 2022 has increased significantly compared to 2021. However, it is necessary to remain vigilant and strengthen hygiene management to ensure environmental hygiene and personnel health in public places.

Objective Analyze and evaluate the measurement uncertainty of phenylethanolamine A residue in beef using liquid chromatography tandem mass spectrometry. Methods By analyzing the detection process and mathematical model, the main sources of uncertainty in the residual amount of phenylethanolamine A are determined: uncertainty caused by detection equipment, uncertainty caused by standard and sample weighing, uncertainty caused by laboratory temperature, uncertainty caused by transfer and constant volume, uncertainty caused by sample pretreatment, and uncertainty caused by experimental repeatability. Results The measurement uncertainty of each component was calculated and the relative standard uncertainty $\left({{u}_{\mathrm{{rel}}}={0.11}}\right)$ was synthesized for the detection of phenylethanolamine A residue in beef by liquid chromatography-tandem mass spectrometry. The expanded uncertainty of the determination results was $\mathrm{U}\left( X\right)={0.11}\mathrm{{gg}}/\mathrm{{kg}}$ . The detection result of measuring phenylethanolamine A in beef by liquid chromatography tandem mass spectrometry was: $X=\left({{0.51}\pm {0.11}}\right)\mathrm{{\mu g}}/\mathrm{{kg}}, k =2$ . Conclusion The detection equipment had the greatest impact on the measurement uncertainty of phenylethanolamine A residue, followed by sample pre-treatment, experimental repeatability, and transfer and constant volume. In daily testing, attention should be paid to the condition of the instruments and equipment, timely verification and calibration should be carried out, the experimental process, transfer and constant volume operation should be standardized, so that to minimize the impact of the above factors on measurement uncertainty as much as possible.

Objective The microbial contamination status of Sanpao Tai series products circulating in the market from 2019 to 2021 was investigated. Methods According to the national food safety standards (food microbiology inspection), the inspection and detection work was carried out from the total number of Colonies, Coliform, Mold, Staphylococcus aureus and Salmonella, and the relevant enterprise standards were collected and analyzed for the results. Results Within three years, 257 batches of samples from Sanpaotai were sampled, among which the total number of Bacterial colonies, Staphylococcus aureus and Salmonella were all qualified batches, while Boliform bacteria and Mold were unqualified, which needed to be paid attention to. Conclusions Mold and its toxins have great harm to human body. In 2021, mold unqualified rate is determined by enterprise standards, and the unqualified rate is decreased. However, considering that some enterprise standards delete mold items and the original value, the situation of mold pollution is still not optimistic.

Objective A method to identify heavy metal outliers in soil of site environmental investigation was studied. Methods First, the normal distribution test of soil heavy metal samples was carried out, then the heavy metal outliers were identified by the PauTa criterion, and the frequency histogram was used to verify the outliers identification results. Results The results of the case study show that the PauTa criterion can effectively identify the outliers of heavy metal content in the soil of the site environmental investigation. Conclusion The use of PauTa criterion to identify the outliers of heavy metal content in soil of site environmental investigation is helpful to identify the soil that is lower than the screening value but greatly affected by human production and life, and can greatly reduce the risk of soil cumulative pollution.

In current technological research and laboratory testing, quality management is crucial to ensuring the reliability of test data, the accuracy of test results, and the repeatability of tests. In order to improve the quality management level of testing laboratories, various quality management system certifications such as CNAS (China National Accreditation Service for Conformity Assessment) and CMA (China Inspection Body and Laboratory Mandatory Approval) have been widely used in laboratories through certification and review processes. The laboratory extensively employs the PDCA cycle (Plan-Do-Check-Act) in quality management. This article explores the application of the PDCA cycle in quality management of testing laboratories and its benefits to laboratory quality management.

With the further development of medical education, surgical laboratory equipment plays an important role in teaching and scientific research. The regular maintenance and overhaul of surgical laboratory equipment is of great significance to guarantee the quality of experimental teaching, prolong the service life of the equipment and reduce the maintenance cost. Laboratory management personnel should be fully aware of this, and take appropriate measures to ensure that the equipment is timely and effective maintenance and overhaul. This paper discusses in detail the regular maintenance and overhaul strategy of surgical laboratory equipment in school. Through analyzing the current situation and problems of equipment maintenance, effective maintenance and overhaul measures are proposed in order to improve the use efficiency and service life of equipment, ensure the stable operation of equipment, improve teaching quality, and ensure the safety of students.

Objective The microwave digestion procedure was not clearly described in the previous standard, which affected the systematic analysis of measurement factors. Methods The heavy metals in municipal sludge was determined by the microwave high-pressure digestion-ICP. A mathematical model for heavy metals measurement in the municipal sludge was established. Results The main sources of uncertainty come from ICP instrument, sample weighing and calibration curve fitting. Conclusion Countermeasures and suggestions for reducing the uncertainty were introduced, which may provided technical basis for improving the accuracy of heavy metals measurement.

Objective To understand the water quality of a remote rural well in a northern city, and to provide rationalized recommendations for the targeted development of a water quality improvement program. Methods The water quality of 32 self-provided wells in the area was sampled during the abundant and dry water periods each year from 2021 to 2023, tested and evaluated in accordance with the Sanitary Standard for Drinking Water (GB/T 5750-2006) and the Hygiene Standards (GB 5749-2006) for testing and evaluation use SPSS 26.0. Results Show that the 192 water samples tested, 144 are qualified, the pass rate is 75.00%. Dry water period pass rate is 84.38%. Abundant water period pass rate is 65.63%. Conclusion The water quality pass rate of a remote rural well in a northern city is lower than the pass rate in the dry season, and the water quality needs to be improved to ensure the safety of drinking water and the health of rural residents.