Objective To establish a method for the detection of cyclicaldehyde compounds in drinking water sources, in order to practice highquality development and improve the technical support of public servicequality. Methods Quantitative detection method of cyclic aldehydecompounds in drinking water by using SPME-GC-MS/MS were established.Results The results show that the optimal conditions for SPME aimed atcyclic aldehyde compounds in drinking water are an incubationtemperature of ${50}^{\circ }\mathrm{C}$ , a rotationalspeed of ${500}\mathrm{r}/\mathrm{{min}}$ , anincubation duration of ${15}\mathrm{\;{min}}$ , followed by asample extraction time of ${20}\mathrm{\;{min}}$ . The detectionlimits of this quantitative detection method were 2.87~4.67 ng/ L, therelative standard deviation were 6%~16%, the recoveries were 70.7%~115%.A specific water sample was collected to ascertain that the keyodor-causing compound was2-EDD, exhibiting concentrations ${32}\mathrm{{ng}}/\mathrm{L}$ . Conclusion This method can accurately and swiftly identify key odor-causingcompounds in drinking water.

The purpose of this paper is to discuss the application of Liquid Chromatography-Mass Spectrometry (LC-MS) in drug quality analysis in order to improve the accuracy and efficiency of drug detection. The basic principle, equipment and application of LC-MS in drug quality analysis are reviewed in this paper. LC-MS technology has shown excellent performance in the qualitative, quantitative, fingerprint and pharmacokinetics of drugs, providing an efficient and accurate tool for drug quality analysis, and has a broad application prospect.

Objective To explore the clinical application value of combined detection of echocardiography, dynamic electrocardiogram, and plate exercise test in the diagnosis of coronary heart disease. Methods 70 suspected coronary heart disease patients were selected and subjected to plate exercise test, dynamic electrocardiogram, echocardiography, and coronary angiography. Analyze the diagnostic performance of each method through ROC curve, and calculate sensitivity, specificity, and AUC values. Results The individual detection AUC values of the three methods were 0.796 (plate exercise test), 0.737 (dynamic electrocardiogram), and 0.773 (echocardiogram), respectively, and the combined detection AUC was 0.826. Conclusion Combined detection can significantly improve the diagnostic accuracy of coronary heart disease, with higher sensitivity and specificity than single detection. It is recommended to widely apply it in clinical practice.

The development of intelligent sensor technology has brought revolutionary changes to all walks of life, especially in the field of industrial production and textile testing to show great potential. Smart sensors are not only capable of sensing physical or chemical quantities in the environment, but also have data processing and intelligent analysis capabilities, making them a significant advantage in textile defect detection. This paper analyzes the basic principle, characteristics and application status of intelligent sensor in industrial production and textile testing. The applications and advantages of different types of intelligent sensors, such as vision, infrared and ultrasonic systems, in textile production are analyzed.

Objective To explore the clinical significance of thecombined detection of fasting blood glucose and glycosylated hemoglobinin the diagnosis and treatment of diabetes. Methods From January 2023 toJanuary 2024,50 healthy people in our hospital were selected as thecontrol group, and 50 diabetes patients in our hospital at the same timewere selected as the observation group. Compare the fasting bloodglucose (FPG), glycated hemoglobin (HbA1c) levels, HbA1c, FPG, and oralglucose tolerance test (OGTT) blood glucose test results, combined andsingle test results after 2 hours of OGTT glucose administration, aswell as the correlation between HbA1c and FPG in the observation group.Results The blood glucose levels, HbA1c, and FPG of the observationgroup after 2 hours of OGTT administration were higher than those of thecontrol group $\left({P<{0.05}}\right)$ . The observation group showed a positivecorrelation between HbA1c and FPG $(r={0.608}$ , $P <{0.05}$ ).The specificity, sensitivity, and accuracy of HbA1c and FPG combineddetection are superior to single detection $\left({P <{0.05}}\right)$ . Conclusion The combined detection of HbA1c and FPG has high diagnostic accuracy fordiabetes, reduces the rate of misdiagnosis and missed diagnosis, canspeed up the diagnosis of diabetes, is conducive to early treatment, andis worth promoting.

Multi-angle phased array ultrasonic technology has important application value in fatigue crack detection of complex structural parts. In this paper, the basic principle of the technique is summarized first, and then the main difficulties in fatigue crack detection of complex structural parts are analyzed, including complex geometric structure interference, quantitative crack characteristics evaluation and environmental factors. To address these challenges, innovative solutions such as deep learning signal processing, multi-parameter feature extraction and adaptive detection strategies are proposed. This study provides a new idea and direction for the further development of fatigue crack detection technology for complex structural parts.

Objective To analyze the application results offluorescence quantitative reverse transcription-polymerase chainreaction (RT-PCR) in the detection of pathogenic microorganisms. MethodsA retrospective analysis was made of 7502 microbiological test dataexamined in the laboratory of our hospital from January 14th, 2023 toDecember 14th, 2023. Conventional RT-PCR method and fluorescentquantitative RT-PCR method were performed respectively, and the goldstandard was the results of special staining microscopy. The diagnosticefficiency and other indicators of the two test results were analyzed.Results ① The ratio of negative to positive by gold standard was ${490}: {7012}$ , the ratio of negative topositive by conventional RT-PCR was ${479}:{6358}$ , and the ratio of negative to positive by fluorescencequantitative RT-PCR was 488 : 7010. ② The sensitivity, specificity andaccuracy of fluorescence quantitative RT-PCR method were 99.97%, 99.59%and 99.95%, which were higher than that of conventional RT-PCR method,with statisticalsignificance $\left({P<{0.05}}\right)$ . ③ The detection rates of variousmicroorganisms by fluorescence quantitative RT-PCR were 99.91%, 100.00%,100.00%, 99.91%, 100.00%, 100.00%, 99.97%, higher than that byconventional RT-PCR, with statistical significance ( $P <{0.05}$ ). Conclusion Fluorescencequantitative RT-PCR method has high diagnostic efficiency and detectionrate in pathogenic microorganisms, which can provide scientific basisfor doctors’ diagnosis and treatment and can be implemented.

Objective Establishment of a capillary column headspacesampling program for Gas chromatography determination of ethanol residuein Isosorbide Mononitrate sustained-release tablets. Methods A capillarycolumn $\left({{30}\mathrm{\;m}\times {0.320}\mathrm{\;{mm}},{0.25\mu}\mathrm{m}}\right)$ with $6\%$ cyanopropylphenyl-94%dimethylpolysiloxane (or similar polarity) as stationary solution wasused. The starting temperature was ${50}^{\circ }\mathrm{C}$ and maintainedfor $6\mathrm{\;{min}}$ , thetemperature of the detector was ${250}^{\circ }\mathrm{C}$ , thetemperature of the inlet was ${200}^{\circ }\mathrm{C}$ , theequilibrium temperature of the headspace bottle was ${80}^{\circ }\mathrm{C}$ , the equilibriumtime was ${30}\mathrm{\;{min}}$ , theflow rate of nitrogen was $1\mathrm{\;{mL}}/\mathrm{{min}}$ , and thetemperature of the headspace bottle was ${200}^{\circ }\mathrm{C}$ . The shuntratio was ${50}: 1$ . Results Underthe above chromatographic conditions, the retention time of ethanol was $3\mathrm{\;{min}}$ and theconcentration of ethanol was in the range of ${0.43}\sim {10.8\mu}\mathrm{g}/\mathrm{{mL}}$ . The recoveries were ${87.04}\%\sim {94.45}\%,\mathrm{{RSD}}={0.17}\%\left({n = 6}\right)$ .

Objective Explore the method of using gas-phase molecularabsorption spectroscopy to determine the ammonia content in unorganizedexhaust gas emissions. Methods Explore the detection method from theaspects of detection limit, calibration curve, precision and accuracy,and compare it with the national standard method. Results Theexperimental results showed that there was a good linear relationshipbetween ammonia concentration and absorbance within the range of $0 \sim 2\mathrm{{mg}}/\mathrm{L}$ , with acorrelation coefficient of 0.9999 . The detection limit of the methodwas ${0.1}\mathrm{{\mug}}/{10}\mathrm{\;{mL}}$ . By measuring the standard sample andconducting spiked recovery tests on the actual sample, the relativestandard deviation RSD of the experimental results was ${0.3}\%\sim {1.5}\%$ , the relative errorwas $-{0.1}\%\sim {0.6}\%$ , and thespiked recovery rate was ${97.1}\%\sim {99.5}\%$ . Compared with thenational standard method, there is no significant difference in theresults obtained by this method. Conclusion This method does not requirepre-treatment, does not use highly toxic reagents, has stronganti-interference ability, and can accurately detect the content ofammonia in the unorganized discharge sample. Suitable for determiningthe ammonia content in unorganized emission samples

Objective Based on UHPLC-Orbitrap HRMS, combined withQuECHERS pretreatment technology, a rapid screening detection method wasestablished to simultaneously screen and confirm 14 categories of 140illegally added drugs in herbal tea. Methods The sample was extractedwith methanol, and purified by dispersed solid phase extraction withsodium acetate and anhydrous magnesium sulfate, neutral alumina andoctadecyl bonded silica gel, separated by a chromatographic columnWaters BEH ${\mathrm{C}}_{18}\left({{2.1}\mathrm{\;{mm}}\times {50}\mathrm{\;{mm}},{1.7\mu}\mathrm{m}}\right)$ , and gradient eluted by two independentmobile phase systems: ${0.2}\%$ formicacid water $\left({V/V}\right)$ solution $\sim {0.2}\%$ formic acidacetonitrile $\left({V/V}\right)$ solution and water-acetonitrile, Full $\mathrm{{MS}}/{\mathrm{{dd}- {MS}}}^{2}$ mode was used to collect data, the standard curve was prepared byextracting solution from blank sample and the external standard methodwas used for quantification. Results The linear relationship of 20representative quality control compounds was good $\left({{r}^{2}> {0.995}}\right)$ from5.0 to ${200}\mathrm{{ng}}/\mathrm{{mL}}$ massconcentration, the average recovery rateat the three levels of low,medium and high is between 83.1% and 107.3%, the relative standarddeviation is less than 15.6% and detection low limit is between ${0.2}\mathrm{{mg}}/\mathrm{{kg}}$ and ${1.0}\mathrm{{mg}}/\mathrm{{kg}}$ .165 herbal tea samples on the market were determined and results showedthat twelve samples were positive, the positive components werechlorpheniramine, acetaminophen, diclofenac sodium, ibuprofen,dexamethasone acetate, erythromycin and florfenicol. Conclusion Themethod has the advantages of simple operation, high sensitivity andhigh-throughput screening. Is suitable for the detection of illegallyadded drugs in herbal tea and other health foods.