Pseudomonas aeruginosa is a conditional pathogenic bacterium that can colonize the upper respiratory tract of pigs. If infected pigs do not have strong immunity or are in a stress state, it is likely to develop Pseudomonas aeruginosa, leading to diseases such as arthritis and meningitis in pigs, seriously damaging the economic benefits of pig farmers. This is very detrimental to the healthy development of China's pig industry. Considering the importance of early diagnosis for the prevention and control of Pseudomonas aeruginosa, this article analyzes Pseudomonas aeruginosa and focuses on the laboratory detection methods of Pseudomonas aeruginosa, in order to lay a foundation for the comprehensive prevention and control of Pseudomonas aeruginosa.

Drug regulatory authorities in all countries have clear regulations and requirements on the production and quality control of drugs. High performance liquid chromatography (high performance liquid chromatography, HPLC), as one of the important means of drug quality control, is widely used in the development, production and circulation of drugs, to ensure that the quality of drugs complies with the relevant regulations and production specifications. This study analyzed the technical principle and characteristics of HPLC technology, summarized and summarized its application in drug quality analysis, further clarified the application effect and value of HPLC in drug quality analysis, and provided power for drug quality and safety management.

Objective To analyze the reasons for the appearance of special-shaped oil drop image in spot method, broaden the applicability of the spot method, and improve detection efficiency. Methods Ten typical samples with different combinations of facet, cabochon, polished, and frosted were tested by a gem refractometer. The study focused on abnormal oil drop images whichhas no clear boundary between light and dark areas but variations in light and dark areas, as well as the cases that the abnormal oil droplet image did not show changes in light and dark areas but only a small bright spot moving along with the oil droplet image. Results It was indicated that even when abnormal oil droplet images are observed in Spot method, reliable refractive index values of gemstones can still be rapidly obtained. Conclusion This study broadens the applicability of Spot method to obtain refractive index for faceted, fine frosted gemstone, and the determination of refractive indices beyond the range of the refractometer in three specific scenarios.

Objective A method to identify heavy metal outliers in soil of site environmental investigation was studied. Methods First, the normal distribution test of soil heavy metal samples was carried out, then the heavy metal outliers were identified by the PauTa criterion, and the frequency histogram was used to verify the outliers identification results. Results The results of the case study show that the PauTa criterion can effectively identify the outliers of heavy metal content in the soil of the site environmental investigation. Conclusion The use of PauTa criterion to identify the outliers of heavy metal content in soil of site environmental investigation is helpful to identify the soil that is lower than the screening value but greatly affected by human production and life, and can greatly reduce the risk of soil cumulative pollution.

Objective The microwave digestion procedure was not clearly described in the previous standard, which affected the systematic analysis of measurement factors. Methods The heavy metals in municipal sludge was determined by the microwave high-pressure digestion-ICP. A mathematical model for heavy metals measurement in the municipal sludge was established. Results The main sources of uncertainty come from ICP instrument, sample weighing and calibration curve fitting. Conclusion Countermeasures and suggestions for reducing the uncertainty were introduced, which may provided technical basis for improving the accuracy of heavy metals measurement.

With the increasing frequency of scientific research activities in universities, laboratory gas cylinders have both special equipment and hazardous chemicals, making their safe use and management particularly important. This article first analyzes the main problems in the current management of gas cylinders in university laboratories, and then proposes improvement measures from the perspective of gas cylinder users to strengthen safety education and training for gas cylinder users, develop and improve operating procedures for gas cylinder use, and standardize the safety inspection of gas cylinders; propose to audit supplier qualifications from the perspective of managers and standardize source management; carry out graded and classified supervision, and implement a regular inspection system; using information technology to improve management efficiency; intensify the promotion of safety culture and establish a management strategy for benchmark laboratories, aiming to improve the safety of laboratory gas cylinder use and provide reference for laboratory gas cylinder safety management.

Food and drug quality and safety are closely related to the production and life of the people, and food and drug testing institutions bear the important responsibility of food and drug quality and safety. As an important place for food and drug inspection institutions to carry out experimental testing work, chemical laboratories involve many chemical indicators in the process of food and drug random inspection and testing. Whether the chemical indicator parameters are qualified or not has a significant impact on the testing results. Therefore, strengthening the quality control of chemical laboratories in food and drug testing institutions is beneficial to improving the accuracy, timeliness, and effectiveness of experimental testing results. The current food and drug industry is developing rapidly, with various types of food and drugs appearing in society. Food and drug testing technology and methods are also becoming increasingly perfect. However, overall, the tasks undertaken by chemical laboratories are still relatively arduous, and the risks of operating chemical laboratories are relatively high. This article focuses on the analysis of the current situation of quality control in chemical laboratories of food and drug inspection institutions, and then conducts research on the key points of quality control in chemical laboratories for reference by peers in testing.

In the information age, laboratory management is facing new challenges and opportunities. The traditional laboratory management model can no longer fully meet the needs of the information age, so it is necessary to innovate and explore management concepts and practices. This article aims to explore innovative concepts and practical experiences in laboratory management in the information age. By introducing advanced information technology, promoting open innovation, emphasizing performance evaluation and quality management, and cultivating innovative talents, laboratory management can achieve better results and outcomes.

Objective To systematically control the quality of nucleic acid testing laboratories through the HACCP system, in order to improve the quality of nucleic acid testing laboratories and provide reference for effectively formulating quality control strategies for nucleic acid testing. Methods Preliminary exploration of quality control in nucleic acid testing laboratories based on the HACCP system, with a focus on analyzing the monitoring procedures, validation measures, and corrective measures developed by the HACCP system in the stages of nucleic acid sample reception, preparation of reagents, sample nucleic acid extraction, nucleic acid amplification, result interpretation, and nucleic acid testing result reporting. Results By analyzing the testing data December 2021 to December 2022, the results showed that all batches of nucleic acid positive quality control products met the judgment rules, and each batch of experiments was in a controlled state. Statistical analysis was conducted on laboratory data under the HACCP system, calculating their standard deviation, mean, and coefficient of variation. After plotting the box plot, outlier tests were conducted, and it was found that the mean did not produce outliers. Conclusion The application of HACCP system in nucleic acid testing laboratories can effectively control the quality of nucleic acid testing laboratories, comprehensively control important control points of nucleic acid testing laboratories, improve the level and quality of laboratory biosafety,

Hazardous waste from laboratories possesses dangerous characteristics such as toxicity, corrosiveness, flammability, infectiousness, and reactivity. Improper handling of such waste can pose threats to human health and the ecological environment. This article analyzes the problems existing in the management of laboratory hazardous waste and proposes targeted management points to help laboratories avoid potential risks, which is of great significance for the scientific management of laboratory hazardous waste.

In current technological research and laboratory testing, quality management is crucial to ensuring the reliability of test data, the accuracy of test results, and the repeatability of tests. In order to improve the quality management level of testing laboratories, various quality management system certifications such as CNAS (China National Accreditation Service for Conformity Assessment) and CMA (China Inspection Body and Laboratory Mandatory Approval) have been widely used in laboratories through certification and review processes. The laboratory extensively employs the PDCA cycle (Plan-Do-Check-Act) in quality management. This article explores the application of the PDCA cycle in quality management of testing laboratories and its benefits to laboratory quality management.

Objective This paper aims to explore how to introduce the concept of risk management into the laboratory quality control and optimize the laboratory quality management strategy. Methods By analyzing the principle of laboratory quality control and the integration mechanism of risk management and quality control, the deficiencies in standardization of quality control procedures, risk prevention mechanism and data utilization feedback in Chinese laboratories are revealed. Results Based on this, optimization paths such as building standardized quality control procedures, multi-dimensional risk prevention system and data-driven monitoring feedback mechanism are proposed. Conclusion The research shows that integrating risk management into laboratory quality control can significantly improve the quality management level, reduce quality risks, and provide a strong quality guarantee for scientific research.

With the continuous improvement of medical informatization level, the application of Hospital Laboratory Information System (LIS) in the medical field is becoming increasingly widespread. As the core link of hospital laboratory information systems, data transmission's security, stability, and efficiency directly affect the quality and efficiency of medical services. This article first outlines the definition and functions of hospital laboratory information systems, as well as the current development status of LIS systems. Subsequently, an in-depth analysis was conducted on the technical requirements for data transmission in hospital laboratory information systems, including the characteristics of data transmission, security requirements, and optimization directions. Through this study, the aim is to provide useful reference and inspiration for the optimization and development of data transmission technology in hospital laboratory information systems.

With the further development of medical education, surgical laboratory equipment plays an important role in teaching and scientific research. The regular maintenance and overhaul of surgical laboratory equipment is of great significance to guarantee the quality of experimental teaching, prolong the service life of the equipment and reduce the maintenance cost. Laboratory management personnel should be fully aware of this, and take appropriate measures to ensure that the equipment is timely and effective maintenance and overhaul. This paper discusses in detail the regular maintenance and overhaul strategy of surgical laboratory equipment in school. Through analyzing the current situation and problems of equipment maintenance, effective maintenance and overhaul measures are proposed in order to improve the use efficiency and service life of equipment, ensure the stable operation of equipment, improve teaching quality, and ensure the safety of students.

Objective To understand the water quality of a remote rural well in a northern city, and to provide rationalized recommendations for the targeted development of a water quality improvement program. Methods The water quality of 32 self-provided wells in the area was sampled during the abundant and dry water periods each year from 2021 to 2023, tested and evaluated in accordance with the Sanitary Standard for Drinking Water (GB/T 5750-2006) and the Hygiene Standards (GB 5749-2006) for testing and evaluation use SPSS 26.0. Results Show that the 192 water samples tested, 144 are qualified, the pass rate is 75.00%. Dry water period pass rate is 84.38%. Abundant water period pass rate is 65.63%. Conclusion The water quality pass rate of a remote rural well in a northern city is lower than the pass rate in the dry season, and the water quality needs to be improved to ensure the safety of drinking water and the health of rural residents.

Objective To study, discuss and analyze the reasons for deviations in drug test results and find out methods for quality control. Methods 150 drug samples from October 2022 to October 2023 were randomly collected and tested using two methods: UV spectrophotometry and high performance liquid chromatography. The results of the drug samples tested by the two methods were comparatively analyzed. Find out the reasons for deviations in drug test results, and finally conduct further research based on the situation of the drugs to find ways to control drug quality. Results The deviation rate of the drug detected by UV spectrophotometry was 4%, and the deviation rate of the test results obtained by high-performance liquid chromatography was 3.33%. The difference between the groups was not statistically significant (P>0.05). The two methods were used to detect the deviation rate. The deviation rate of drug test results is different, but the difference is not significant. Conclusion There are many factors that cause deviations in drug testing results. To ensure that drug testing results have high accuracy, scientific and reasonable testing methods and technologies must be used to ensure the standardization of operations during testing and reduce the impact of variable factors on The influence of test results can reduce errors, improve the accuracy of test results, maximize the efficacy of drugs, and ensure the quality of drugs.

To avoid major differences in the testing process, help customers correctly understand and use reports, and effectively control risks, according to the relevant requirements of Laboratory Accreditation and Inspection Body and Laboratory Mandatory Approval, combined with practical experience, this paper puts forward 10 aspects that should be agreed in the inspection and testing entrustment agreement, analyzes more than 10 items that should be declared in the inspection and testing report, summarizes the key issues that should be paid attention to, and provides general requirements for the industry to refer to, which has a great practical guiding significance for the standardization of inspection and testing activities.

Objective To optimize the detection ability of Staphylococcus aureus in our laboratory by participating in the verification of the detection ability of Staphylococcus aureus in cosmetics organized by the Test and Evaluation Center of Chinese Academy of Inspection and Quarantine. Methods The samples were tested according to the test instructions of ACAS-PT1637 (2023) for the detection ability of Staphylococcus aureus in cosmetics and the Technical Specification for Cosmetic Safety (2015 edition). At the same time, the conventional biochemical detection methods, ATB bacteria identification and fluorescence quantitative PCR amplification were used to detect. Results Staphylococcus aureus was not detected in sample 23-Q777 and Staphylococcus aureus was detected in sample 23-A973. The result of this ability verification is satisfactory. Conclusion By participating in this capability verification, the laboratory not only improved the detection ability of the bacteria, but also effectively demonstrated that the laboratory has the ability to detect Staphylococcus aureus in cosmetics by using a variety of methods.

Objective The microbial contamination status of Sanpao Tai series products circulating in the market from 2019 to 2021 was investigated. Methods According to the national food safety standards (food microbiology inspection), the inspection and detection work was carried out from the total number of Colonies, Coliform, Mold, Staphylococcus aureus and Salmonella, and the relevant enterprise standards were collected and analyzed for the results. Results Within three years, 257 batches of samples from Sanpaotai were sampled, among which the total number of Bacterial colonies, Staphylococcus aureus and Salmonella were all qualified batches, while Boliform bacteria and Mold were unqualified, which needed to be paid attention to. Conclusions Mold and its toxins have great harm to human body. In 2021, mold unqualified rate is determined by enterprise standards, and the unqualified rate is decreased. However, considering that some enterprise standards delete mold items and the original value, the situation of mold pollution is still not optimistic.