Objective To establish the method of microbial limit test of Fufang Huangliansu tablets. Methods According to the provisions of Part Four of the 2020 edition of the Pharmacopoeia of the People's Republic of China, the applicability test of microbial limit testing methods shall be gradually carried out using methods such as plate pouring method, increasing dilution ratio, and dilution combined with membrane filtration. Results The membrane filtration method was used for aerobic bacteria counting. The medium dilution method was used for counting total combined molds and yeasts. The direct inoculation method was used for three types of control bacteria that must be tested according to drug standards. Conclusion The microbiological limit test method for this drug proposed in this experiment is simple and easy to implement.

Inter-cresol is a common environmental pollutant and industrial raw material, and its sensitive, accurate and rapid detection is crucial for environmental monitoring and food safety. Molecularly imprinted polymers (Molecularly Imprinted Polymers, MIPs) have shown an attractive application prospect in improving the detection method due to their unique molecular recognition ability. This paper systematically discusses the application of MIPs technology in improving detection sensitivity, simplifying sample processing and enhancing selective identification, and puts forward a series of innovative imprinting strategies and detection schemes, in order to provide new ideas and methods for solving the current technical bottleneck in parcresol detection.

Drug testing is a professional work, which contains many details, any link will affect the efficiency and quality of the overall work. High performance liquid chromatography (HPLC) has the characteristics of high sensitivity, short test time and wide application range. Its application in drug testing can improve the shortcomings of traditional testing techniques and make the test results more reliable and accurate. This paper first describes the concept of high performance liquid chromatography, then analyzes the characteristics of high performance liquid chromatography, including short detection time, high sensitivity and wide application range, and then analyzes the value of practicing high performance liquid chromatography in drug testing, including timely detection of drug processing problems, ensuring drug safety, and promoting the improvement of drug testing technology. Finally, the application of high performance liquid chromatography in drug testing was discussed.

Objective Measurement uncertainty is a parameter closely related to the measurement results and is indispensable for the quality control of laboratory data. In this paper, we analyze the source of the uncertainty of sulfur dioxide emission concentration in the exhaust of fixed pollution sources, find out the various uncertainty components affecting the measurement results, and conduct the analysis and evaluation of the measurement uncertainty, so as to provide an important reference for the analysis and judgment of the accuracy of environmental monitoring data and calibrate the results. Methods The concentration of sulfur dioxide emission in fixed pollution waste gas is measured according to UV absorption method. Results The extended uncertainty of the resulting determination was 6.9%. Conclusion The uncertainty component introduced by the instrument system effect is relatively large. In addition to regular sending to the technical supervision department for verification, the user of the instrument should also carry out regular maintenance and necessary period verification to ensure the accuracy of the instrument and the repetition of the measurement.

Promethazine hydrochloride has good effects on skin, ear, nose, and throat, as well as internal medicine diseases. Therefore, it is widely used in clinical pediatrics. Due to its large size, the use of this drug in clinical pediatric medicine is limited to some extent. Excessive content of promethazine hydrochloride tablets can easily cause adverse reactions, so it is necessary to analyze the content of promethazine hydrochloride tablets in order to adjust the medication deviation. High performance liquid chromatography can combine pharmacokinetics to analyze the actual content of drugs. With its advantages of high sensitivity and specificity, it has been widely applied in drug analysis in recent years. High performance liquid chromatography is based on the application scope of drugs, forming a comprehensive chromatographic drug analysis plan, timely adjusting chromatographic phase changes, and conducting scientific evaluations to enhance separation efficiency and accurately determine drug content, in order to optimize the application of drug components in high-performance liquid chromatography analysis. This study mainly reviews the research on the determination of the content of promethazine hydrochloride tablets in children's medication by high-performance liquid chromatography, in order to provide reference for the rational use of drugs in pediatric clinical practice.

Aspirin is a commonly used drug in clinical practice, which is well-known to the public for its precise therapeutic effect and minimal adverse drug reactions. Based on the research results of aspirin content determination methods in recent years, this paper introduces the research progress of titration, ultraviolet and visible spectrophotometry, high performance liquid chromatography, near infrared diffuse reflectance method, etc. in determining aspirin content, providing a reference basis for further developing new detection methods for aspirin.

Objective To determine the quality of broad hawthorn from different origins and provide a basis for scientifically formulating quality standards for hawthorn medicinal materials. Method According to the General Principles of the Four Parts of the 2015 edition of the Chinese Pharmacopoeia, microscopic and thin-layer chromatography identification was performed on hawthorn from different origins; Detect moisture and ash extracts. Result There are certain differences in the quality of hawthorn from different regions. Conclusion The microscopic and thin-layer identification of hawthorn and the detection of its indicator components can serve as a standard for controlling the quality of hawthorn medicinal materials.

Since the safety of medical university laboratories is affected by many factors and shows a trend of increasing installation hazards, this paper establishes a medical university laboratory safety evaluation system based on hierarchical analysis-fuzzy comprehensive evaluation method by combining the results of various scholars on the research of laboratory safety evaluation system in colleges and universities. And through the evaluation system of a college laboratory safety evaluation to the evaluation of the scientific analysis, the results show that through the evaluation system can get more objective safety evaluation results.

This overview discusses in detail the key role of inspection and testing laboratories in technological innovation and quality management. Firstly, technological innovation is an essential tool for laboratories to enhance their testing capabilities and technical standards, and it is also the core driving force for their sustainable development. Secondly, quality management is the core aspect of ensuring the accuracy and reliability of testing reports issued by inspection and testing laboratories. Labs need to establish a scientific and standardized quality management system and continuously improve it. At the same time, the China National Accreditation Service for Conformity Assessment (CNAS), as a signatory of international mutual recognition agreements, has put forward explicit requirements for the management of personnel capabilities in inspection institutions. Furthermore, chemical metrology technology faces new development and challenges. This article will delve into these important topics.

With the booming development of China's medical and health care, China's livelihood issues have been safeguarded, but the quality and safety of medical devices put forward higher requirements. The laboratory of medical device testing organisations is responsible for testing the quality and safety of medical devices, in the implementation of national mandatory standards, but also to have a reasonable management of the laboratory, how to better play the role of the laboratory of medical device testing organisations, in order to provide accurate, scientific and efficient test results. Therefore, this thesis takes standardised management as the research concept, through the analysis of the current situation and content of the management of the laboratory of the medical device inspection agency, to find out the problems that may occur in the process of its operation, and put forward the corresponding improvement measures for these problems.

Continuous improvement and quality assurance in laboratories are two crucial aspects of laboratory management, which complement and are inseparable. This article delves into the concepts, methods, and roles of the two, revealing their importance and interrelationship in laboratory management by analyzing successful and failed cases. Quality assurance plays multiple roles in the laboratory, including ensuring the accuracy and reliability of experimental results, improving experimental repeatability and consistency, risk management and error prevention, and promoting continuous improvement. Continuous improvement is the continuation of quality assurance, by constantly seeking optimization, improving efficiency, and introducing innovation, enabling laboratories to adapt to constantly changing needs and technological environments. Based on case analysis, we have drawn a series of conclusions that emphasize the importance of continuous improvement and quality assurance in the laboratory, as well as the foundation they jointly lay for the stable operation and continuous progress of the laboratory.

Talent cultivation is a crucial link in the efficient operation of laboratory systems. This article analyzes the constituent elements and operational mechanisms of laboratory systems, focusing on the significant role of talent cultivation in enhancing the management of inspection and testing institutions and fostering innovative thinking. Additionally, the article proposes innovative strategies for talent cultivation, including project-driven scientific research training, interdisciplinary cross-cooperation platforms, educational reinforcement, regular evaluation, and dynamic adjustments, aiming to provide references for the optimization and improvement of talent cultivation systems in laboratory settings in the context of the new era.

In the current era of science and technology, chemical laboratory has become an indispensable part of scientific research and industrial production. The laboratory is not only the frontier to promote scientific discovery and technological innovation, but also an important place to cultivate future scientists. Laboratory safety is the priority of laboratory management, with the new situation of the chemical experiment increasingly diversified, chemical laboratory safety faces many new problems, this paper from the research and practice of the chemical laboratory safety management system, expounds the new situation of the chemical laboratory safety management system problems and countermeasures.

Objective This study aims to investigate the impact of laboratory personnel training and skill enhancement on quality management. Methods By analyzing key elements of laboratory quality management, it emphasizes the importance of standard operating procedures (SOPs), quality control (QC) and assurance (QA) measures, and highlights the necessity of professional training and ethical education. Results Utilizing a case study from a pharmacokinetics laboratory in Shanghai, the research finds that targeted training programs significantly improve the accuracy of experimental data, reduce variability, and enhance research quality. Conclusion The results underscore the critical role of systematic training and skill development in achieving effective quality management, making a significant contribution to the advancement of scientific research.

Large instruments and equipment provide an important material foundation for teaching, research and talent cultivation in universities. Promoting the open sharing of large instruments and equipment and improving the efficiency of instrument use is the focus of large instrument and equipment management. The paper combines the practice of Central South University to build an open sharing mechanism, including the construction of university-level public platform to promote centralized and intensive management; optimize the shared service platform to promote the transformation of service mode; strengthen the assessment and evaluation of instruments, focusing on the use of assessment results; strengthen the construction of talent team to mobilize the enthusiasm of experimental personnel.

Geological experimental testing is an important task in mineral resource development, but many problems have been exposed in the traditional testing mode, resulting in low overall work efficiency and difficulty in effectively managing various experimental testing data. In recent years, with the continuous improvement of laboratory informatization level, the application of laboratory information management system as a new attempt in geological experiment testing has achieved good results. The use of information technology can more efficiently manage various data, improve management efficiency and accuracy, and thus promote the development of geological experiment testing work. This study mainly discusses the application of laboratory information management system in geological experiment testing, aiming to improve the efficiency of laboratory management, optimize the experimental test process, and improve the quality and reliability of experimental data by means of information technology. Through the application of the laboratory information management system, it can not only realize the effective integration and utilization of laboratory resources, but also improve the safety management level of the laboratory and the work efficiency of the experimental personnel, which has important practical significance.

Rock and mineral analysis and testing play a crucial role in geological research, and are directly related to the quality and efficiency of geological work. However, rock and mineral analysis and testing work has strong professionalism and technicality, and is easily affected by various factors in practical operation, resulting in inaccurate results of rock and mineral analysis and testing, which cannot provide effective reference for geological exploration and mineral resource evaluation. Therefore, this article first elaborates on the importance of rock and mineral analysis in the geological chemistry laboratory, then analyzes the existing problems in rock and mineral analysis and testing in the geological chemistry laboratory, and finally delves into effective measures to improve the rock and mineral analysis and testing capabilities of the geological chemistry laboratory.

Objective This article aims to explore in detail the problems faced by medical laboratory laboratories in universities in terms of biosafety protection, and propose effective response strategies. Through in-depth analysis of laboratory equipment and facilities, personnel training, safety procedures and protocols, emergency response, and safety culture, this article aims to improve the safety performance of the laboratory. Method By evaluating the existing safety measures of medical laboratory in universities, identify key safety hazards. Emphasis has been placed on the modernization needs of equipment and facilities, personnel safety awareness and skill training, the development and implementation of strict safety procedures and protocols, and the establishment of effective emergency response mechanisms. Result In response to the identification issues, this article proposes a series of comprehensive solutions, including but not limited to updating laboratory equipment, strengthening personnel training, developing strict safety procedures, establishing sound emergency response mechanisms, and actively cultivating safety awareness within the laboratory. These solutions aim to improve the overall biosafety level of the laboratory, ensuring the safety and efficiency of research work. Conclusion It emphasizes the importance of continuously monitoring and updating laboratory safety measures. By implementing these strategies, not only can current security issues be addressed, but also new challenges that may arise in the future can be prepared to ensure a safe, efficient, and productive experimental environment.

Based on the primary inspecting and testing institutions, combined with the actual work, this paper discusses some common problems such as the development position, encouragement and incentive mechanism, talent team construction, scientific and technological innovation, scientific and technological achievements transformation of the current market supervision system from the aspects of quality infrastructure construction, scientific and technological innovation, and a number of suggestions are given.

Objective This paper focuses on the collaborative optimization of on-site detection technology and quality control systems in occupational hygiene. Methods By comprehensively analyzing traditional and modern detection methods, as well as the construction and management of quality control systems, the paper reveals the technological challenges and trends in the modern industrial environment. Results Strategies such as the application of advanced detection technology in quality control, optimization of data integration and analysis, construction of intelligent decision support systems, and the design of collaborative workflows are proposed to comprehensively enhance the efficiency of occupational hygiene detection. Conclusion The research of this paper provides robust support for the technological development and quality control practices in the field of occupational hygiene.

Objective Reasonably set up and implement the measurement and calibration scheme of the yoke magnetic particle flaw detector, including calibration demand analysis, calibration preparation, calibration implementation, calibration work after calibration, calibration summary and analysis, etc., to improve the lifting force, safety, permeability and sensitivity of the yoke magnetic particle flaw detector. Methods Taking the CDX-III magnetic yoke magnetic particle flaw detection machine as an example, the calibration implementation preparation, working environment simulation, power inspection, insulation resistance and strength test, current error test, current measuring device access, sensitivity detection and other specific schemes were reasonably designed. Experimental research method was adopted to analyze the rationality of the calibration scheme through experimental results. Results Through the use of this measurement calibration scheme, the lifting force, safety, permeability and sensitivity of the yoke magnetic particle flaw detection machine can be improved to meet the national metrology standards and requirements. Conclusion This measurement calibration scheme has systematic and fine characteristics, and pays attention to the use of environmental simulation, enhance its practicality and rationality, more comprehensive and accurate, worthy of promotion and use.

Metrology is an important engineering discipline that covers the knowledge and technologies in such aspects as measurement, standardization, calibration and quality control. Nowadays, metrology management has become critical in industrial and scientific research fields for it helps ensure the accuracy, traceability and repeatability of products and data. The objective of this paper is to explore the basic principles of metrology management and introduce the software tools widely used in this field, so as to help Metrology Engineers better manage measurement and quality control processes.

Objective In order to increase the supervision of asarone injection and ensure the safety of clinical use, the samples of asarone injection in circulation in the market were tested. Methods In this paper, according to the national drug standards approved by the State Food and Drug Administration, the quality of 26 batches of asarone injection sampled by the institute was investigated, and the project evaluation of the variety traits, identification, pH value, color, related substances, loading, visible foreign bodies and content determination was completed. Results 26 batches of asarone injection were tested according to the standard, and all items were in conformity with the regulations. Conclusion The overall quality of this variety is good, but the properties of light degradation are observed. It is suggested to further optimize the production and use conditions, reduce the exposure time and avoid the formation of impurities.

Objective Discussion on the dilution of sulfur dioxide blank solution for determination of high-concentration sulfur dioxide samples. Methods Several experiments are done to Sulfur dioxide standard solution as sample. For the high concentration of sulfur dioxide exceeds the upper limit of the standard curve of absorbance (referred to as the out of sample, the same below), diluted with sulfur dioxide reagent blank solution (referred to as the blank solution, the same below) and then determination. Results The experimental results show that the absorbance of the sample, preferably not more than the upper limit of the standard curve is 0.100. Conclusion The dilution ratio should not be greater than 2 times; shake well placed 4-5 minutes after the determination as well; sulfur dioxide dilution and measured were lower than sulfur dioxide due to overloading, the samples should be more than the maximum absorbance value according to appropriately increase the sample number measured 4%-8%, make the results more close to the actual value.