To analyze the coupling and coordination relationship between the supply of medical resources and the utilization of medical services in Chengdu-Chongqing economic circle from 2016 to 2021, so as to provide reference for optimizing the allocation of medical resources.

Based on the comprehensive evaluation index system of medical resources supply and service utilization, a comprehensive evaluation model and a coupling coordination degree model were constructed to analyze the coupling and coordination relationship between medical resources supply and service utilization in Chengdu-Chongqing economic circle from 2016 to 2021. With the use of exploratory spatial data analysis, the spatial-temporal evolution characteristics of medical resources coupling coordination were analyzed.

From 2016 to 2021, the development levels of medical resources supply and service utilization in Chengdu-Chongqing economic circle were 0.11-0.13 and 0.14-0.15, respectively, and the relative degree of development changed from shortage of medical resources (0.78) to mutual complement and promotion of development (0.92). However, the proportion of cities subject to lagging supply of medical resources was still large (68.8% in 2021). The level of coupling coordination changed from 0.47 to barely coordinated development. By 2021, only Chongqing and Chengdu had a good coordinated development. The LISA diagram showed that the “high-high” areas increased year by year, and the “cold point” effect disappeared, but there was still a “highland” phenomenon centered on Nanchong.

The development level of medical resource supply and service utilization in Chengdu-Chongqing economic circle is stable and rising, but the overall level is low and the regional gap is obvious. The coupling coordination level needs to be further improved, which is mainly limited by the lagging supply of medical resources. The spatial positive correlation of coupling coordination degree is gradually enhanced, but the spatial heterogeneity is still prominent.

To Chinesize the Nursing Home Care-related Quality of Life Scale (NHC-QoL) and to test its reliability and validity.

According to the Brislin model, the NHC-QoL scale was translated into Chinese and cross-cultural debugging was carried out. Using convenience sampling method, 198 elderly people from 4 nursing institutions in Shiyan city were investigated by questionnaire from March to July 2023 to evaluate the reliability and validity of the scale.

There were 14 items in the Chinese version of NHC-QoL. The content validity index of each item was 0.7-1.0, and the content validity index of the scale was 0.929. Exploratory factor analysis extracted 5 common factors, which could explain 67.914% of the total variation.After discussion within the research group, the common factors were reduced to 2 common factors namely environment and service (11 items) and social interaction (3 items). The total Cronbach’s α coefficient of the scale was 0.758 and the test-retest reliability was 0.783.

The Chinese version of NHC-QoL scale has good reliability and validity and can be used to evaluate the quality of life of the elderly in nursing institutions.

To explore the mutual predictive relationship between mobile social media Fear of Missing Out (FoMO) and Mobile Phone Addiction (MPA) among vocational college students, to provide scientific reference for the prevention and education of college students’ mobile phone addiction behavior.

With the use of cluster random sampling, 1 000 college students from a vocational college in Shenzhen were investigated by mobile social media FoMO scale and MPA scale in September 2021 (T1) and December 2021 (T2). The data were analyzed by cross-lag regression analysis.

There was a significant positive correlation including the synchronous correlation and the consecutive correlation between mobile social media FoMO and MPA (P<0.05). Mobile social media FoMO T1 positively predicted MPA T2 (β=0.25, P<0.001), whereas MPA T1 did not predict mobile social media FoMO T2 (β=-0.01, P=0.76). Three dimensions of mobile social media FoMO could predict MPA synchronously (P<0.05) and behavioral performance T1 could predict MPA T2 consecutively (P<0.05). Two dimensions of MPA,loss of control and avoidance, could predict mobile social media FoMO synchronously (P<0.05), and avoidance T1 could predict mobile social media FoMO T2 consecutively (P<0.05).

Vocational college students with higher FoMO are more likely to have MPA. There is a one-way predictive relationship between mobile social media FoMO and MPA.

To understand the current situation and characteristics of chronic disease comorbidities among the elderly living alone in China, to analyze their comorbidity patterns, and to explore the relationship between health-related behaviors and chronic comorbidity in the elderly living alone, so as to provide basis for co-prevention and co-management of multiple diseases in the elderly.

Based on the data of the 2018 Chinese longitudinal healthy longevity survey (CLHLS), the network map was used to identify the common binary co-disease patterns of chronic diseases in the elderly living alone, and the Gephi software was used to visualize the chronic disease co-disease network of the elderly. Using Apriorism algorithm, the association rules were used to analyze the correlation between health-related behaviors and co-diseases of the elderly living alone, and multi-factor Logistic regression model was used to analyze the correlation between chronic diseases and health-related behaviors of the elderly living alone.

A total of 1 905 elderly people living alone over 65 years were included, of whom 766 suffered from two or more chronic diseases, and the co-morbidity of chronic diseases was 40.2%. A total of 45 meaningful binary co-disease patterns with strong links were identified through network map analysis, of which 10 were related to hypertension and 7 were related to heart disease. The strong association rules among the association rules of health-related behaviors and co-diseases of the elderly living alone were poor sleep quality, no physical activity, no exercise, and no outdoor activity. The multivariate Logistic regression model showed that the elderly living alone with smoking (OR=1.791, 95%CI: 1.205-2.664) and alcohol consumption (OR=1.597, 95%CI: 1.084-2.353) had an increased risk of chronic co-disease compared with those without chronic diseases. Elderly people living alone with exercise (OR=0.132, 95%CI: 0.100-0.175), outdoor activities (OR=0.047,95%CI: 0.035-0.063), good sleep quality (OR=0.469, 95%CI: 0.319-0.688), and adequate sleep (OR=0.648, 95%CI: 0.484-0.867) had a lower risk of chronic comorbidity.

The comorbidity pattern of the elderly living alone in China is complex and related to health-related behaviors. The risk of comorbidity in the elderly can be reduced by improving health-related behaviors, such as increasing exercise and outdoor activities and adjusting sleep duration and sleep quality.

To explore the relationship among cognitive function, anxiety, and self-management behavior in elderly patients with diabetes mellitus.

A face-to-face survey was conducted among elderly patients with type 2 diabetes mellitus aged 60 and over in the Department of Endocrinology, Penglai People’s Hospital, Yantai city, Shandong Province from October 2021 to May 2022. The Geriatric Anxiety Inventory-Short Form (GAI-SF), the Montreal Cognitive Assessment (MoCA),and self-designed items were used to assess the anxiety, cognitive function, and self-management behaviors of the patients.Path analysis and mediation effect testing were conducted using a structural equation model.

In total 1 319 diabetic patients aged 60 and above were enrolled, of whom 8.3% had anxiety symptoms. The average scores of MoCA scale and self-management behavior were (23.89±4.12) and (3.74±1.27), respectively. Structural equation model analysis showed that cognitive function had a masking effect between anxiety and self-management behavior, and anxiety had a positive effect on self-management behavior directly (β=0.127, P < 0.019). However, it also had a strong negative effect on cognitive function (β=-0.567, P < 0.001) and then had a negative effect on self-management behavior (β=-0.241, P < 0.001). Therefore, anxiety had a negative effect on self-management behavior (β=-0.115, P < 0.001).

The anxiety of elderly patients with diabetes is negatively correlated with their self-management behavior and can have a negative effect on self-management through cognitive function.

To understand the current status of knowledge and willingness of influenza vaccination among the unvaccinated elderly people in a southwestern city, and to analyze the factors affecting the willingness of influenza vaccination, so as to provide a basis for promoting the popularization of influenza vaccine.

A total of 600 elderly people aged 60 and above who were not vaccinated with influenza vaccine from October to December 2023 were surveyed on their knowledge and willingness to be vaccinated with influenza vaccine. Finally, 538 valid questionnaires were collected. Univariate analysis was carried out using t-test and χ² test, and logistic regression model was used to analyze influenza vaccination intention.

In total 57.8% of the 538 elderly people were willing to be vaccinated against influenza. Specifically, 55.6% of the elderly “did not know or have not heard of the influenza vaccine”, 53.2% of the elderly believed that “the influenza vaccine may not be effective”, 67.5% of the elderly believed that “influenza vaccination would have side effects”, and the estimated proportion of side effects was at 17.53%. The results of multivariate analysis of influenza vaccination willingness showed that people who had “general knowledge” (OR=2.464, 95%CI: 1.209-5.019, P=0.013) and who were “very knowledgeable” (OR=2.885, 95%CI: 1.112-7.485, P=0.029) were more likely to be vaccinated than those who had not heard of influenza vaccine.Compared with the “estimated proportion of influenza vaccination in people aged 60 and over < 20%” group, the “estimated vaccination ratio of 60% to 80%” group (OR=3.478, 95%CI=1.555-7.779, P=0.002), and the “estimated vaccination ratio ≥80%” group (OR=4.591, 95%CI=1.058-19.915, P=0.042) had higher willingness to vaccinate influenza vaccine. The higher the score of satisfaction with personal health, the lower the willingness to be vaccinated against influenza (OR=0.804, 95%CI=0.670-0.964, P=0.018).

The elderly people who have not been vaccinated with influenza vaccine in this area do not know enough about influenza and its vaccine, and the willingness of influenza vaccination is low, which needs to be improved urgently. It is suggested that the knowledge and publicity of influenza and its vaccine be strengthened in this region, and practical vaccination strategies should be adopted to improve the willingness and vaccination rate of influenza vaccination.

To investigate the epidemiological characteristics and pathogen distribution of burn patients at the hospital.

The medical records of 2 434 burn patients who met the inclusion criteria in the First Affiliated Hospital of Anhui Medical University from 2019 to 2022 were analyzed, including sex, age, injury factors, burn site, burn severity, and seasonal distribution of burns, as well as the type of pathogen of infection, the source of tissue/body fluid and its drug resistance. The species of pathogens were identified by Matter-assisted Laser Desorption Time-of-flight Mass Spectrometry (VITEK-MS), and the drug sensitivity of the top three pathogens was determined by VITEK2 Compact. SPSS27.0 and WHONET5.6 statistical software were used to analyze the data.

A total of 2 434 burn patients were enrolled in this study, with a male-to-female ratio of 2.2915. The average age was 29.8 ±25.95 years old. Adults and the elderly were most likely to have burns in summer, while children were more likely to suffer from burns in spring. Hot water scald was the main cause of disease. A total of 952 strains of pathogenic bacteria were collected, all of which were isolated for the first time. The top five pathogens were Pseudomonas aeruginosa, Acinetobacter baumannii, Staphylococcus aureus, Klebsiella pneumoniae, and Enterobacter cloacae. The number of pathogens isolated from wound secretions was the largest, accounting for 83.93% (799/952). The resistance rate of Pseudomonas aeruginosa to the first and second generation cephalosporins was 100%, but the resistance rate to aztreonam, tobramycin,and piperacillin decreased. The resistance rates of Acinetobacter baumannii to polymyxin B, minocycline, and tigecyclines were all 0, and the resistance rates to other antibiotics were all ≥ 50.0%. The resistance rate to penicillin and Staphylococcus aureus was more than 90%, but it was completely sensitive to vancomycin, linezolid, tigecyclines, and ampicillin/sulbactam.

Based on the age range division, there are significant differences in gender, cause of injury, prehospital treatment, burn severity, and burn site. Scald is the main cause of injury, limbs are the most prone to burn, and cases occur in summer most commonly. The main pathogen of burn infection is Pseudomonas aeruginosa, which mainly comes from wound secretions.

To analyze the transmission of HIV-1 infections newly found in Luzhou city, Sichuan Province in 2021,and to investigate the risk factors and characteristics of HIV-1 transmission network, so as to provide data for the prevention and control of AIDS epidemic in Luzhou.

The blood samples and demographic information of 363 newly reported HIV-1 infections in Luzhou in 2021 were collected. The HIV-1 pol gene sequence was amplified by nested PCR, and the virus subtype and transmissible drug resistance were analyzed according to the pol gene sequence. The molecular network was constructed based on the optimal gene distance (d=1.5%) and the characteristics of molecular transmission network and its influencing factors were analyzed.

A total of 346 valid sequences were obtained, including 113 cases of CRF07_BC subtype (32.66%),107 cases of CRF01_AE subtype (30.92%), 99 cases of CRF08_BC subtype (28.61%), 18 cases of CRF105_0108 subtype (5.20%), and 9 cases of other subtypes (2.60%). The rate of transmitted drug resistance of HIV-1 was 15.03% (52/346), and dual drug resistance was detected in 4 samples. A total of 34 molecular clusters were formed, and the number of cases in the clusters ranged from 2 to 25, with 148 individuals (42.77%) included in the transmission network under the optimal genetic distance threshold (1.5%). There were significant differences in age, education level, infection route, genotype, and registered residence registration (P<0.05). Logistic regression found that education level and registered residence were the influencing factors of network access.

The newly reported HIV-1 infection in Luzhou city shows diversity of virus genes. CRF01_AE,CRF07_BC, and CRF08_ BC subtype have become the main subtype of epidemic virus strains, and molecular transmission network should be established for long-term monitoring in this region to take targeted measures to block its further transmission.

To analyze the basic hygiene status and main health hazard factors of public places in Hainan Province, so as to provide technical support for promoting health management of public places.

The health hazard factors of 200 public places in Hainan Province were monitored in 2022, and the results were statistically analyzed.

A total of 2 339 samples from public places in Hainan Province were monitored, and the overall qualified rate was 83.9%. There were significant differences in the qualified rates of samples from different types of places (χ²=120.63, P < 0.05). Among them, the qualified rates of swimming pools (halls) and hotels (hotels) were relatively low, which were 65.8% and 76.3%, respectively, while the overall qualified rates of the other five types of places were between 85.7% and 96.5%. The main unqualified indexes of indoor air in hotels were formaldehyde, the total number of bacteria, PM₁₀, and PM_2.5. The main unqualified indexes of indoor air in barber shops and beauty shops were ammonia and PM₁₀. The main unqualified index of indoor air in shopping malls (supermarkets) was the total number of bacteria. The total number of bacteria detected in all kinds of public goods and appliances in 6 types of public places exceeded the limit. The unqualified rate of pH value of towels in hotels, beauty shops, and barber shops was 43.2%, 13.6% and 11.4%, respectively. The main unqualified indexes of swimming pool were the pH value of swimming pool water, urea and oxidation-reduction potential, and the unqualified rate of oxidation-reduction potential was 29.6%.

The hygienic condition of public places in Hainan Province still needs to be improved in 2022. It is suggested that the relevant departments further strengthen the supervision and monitoring of the total number of bacteria, ammonia, PM₁₀, PM_2.5 and formaldehyde in indoor air, the total number of bacteria, coliform group and pH value of towels for public goods, and the redox potential, urea and pH value of swimming pool water.

To understand the detection of four prohibited veterinary drugs of fresh and live freshwater fish sold in Guangzhou by analyzing the test data from risk monitoring and supervision sampling, so as to provide reference basis for food safety supervision.

Through the Guangzhou Food Safety Risk Monitoring system and the Food Safety Supervision and Inspection Public Information report of Guangzhou Market Administration, the test results of fresh water fish samples collected from supermarkets, markets, and online e-commerce in Guangzhou from 2017 to 2021 were obtained. The detection of nitrofuran drugs, chloramphenicol, sodium pentachloro phenate, and malachite green drugs were analyzed.

The total detection rate of banned veterinary drugs in risk monitoring samples was 35.3% (84/238), and that in supervised sampling samples was 3.10% (118/3 806). The banned veterinary drugs with high detection rates of the two data sources were different. The risk monitoring rates of chloramphenicol and sodium pentachloro phenate were 17.23% (41/238) and 17.23% (41/238), respectively, and that of malachite green was 2.18% (83/3 806). The drug detection rate of the samples collected by risk monitoring in the network e-commerce link was 47.50% (19/40), which was the highest among all sampling links. The results of the two data sources showed that the detection rate of banned veterinary drugs in the wholesale market was high: 47.37% (18/38) and 4.13% (5/121),respectively.

The results of data analysis from the two sources complement each other and jointly reveal the problem of banned veterinary drug residues in fresh freshwater fish sold in Guangzhou from 2017 to 2021. It is suggested that the relevant departments pay more attention to the illegal use of chloramphenicol, sodium pentachloro phenate, and malachite green drugs.