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The chain mediating effects of activities of daily living and depression on self-rated health among empty-nest elderly with chronic disease comorbidity
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Xin SUI, Wen-chao WANG, Yun-na GONG, Yun-long JIAN, Li-qin SONG, Xiao-lin ZHANG, Yong MA
Modern Preventive Medicine | 2026, 53(1) : 142 - 147
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Modern Preventive Medicine | 2026, 53(1): 142-147
• Health and Social Behavior •
The chain mediating effects of activities of daily living and depression on self-rated health among empty-nest elderly with chronic disease comorbidity
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Xin SUI, Wen-chao WANG, Yun-na GONG, Yun-long JIAN, Li-qin SONG, Xiao-lin ZHANG, Yong MA
Affiliations
  • School of Management, Shandong Second Medical University, Weifang, Shandong 261053, China
Published: 2026-01-10 doi: 10.20043/j.cnki.MPM.202507408
Outline
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Objective

To explore the mediating role of activities of daily living (ADL) and depression between chronic disease comorbidity and self-rated health in empty-nest elderly, and to provide a reference for improving the self-rated health and quality of life of empty-nest elderly.

Methods

A total of 3 542 empty-nest elderly aged 60 years and older from the 2020 China Health and Retirement Longitudinal Study were selected as study subjects. Spearman’s correlation analysis was employed to explore the associations between chronic disease comorbidity, ADL, depression, and self-rated health among empty-nest elderly. The Process 4.1 plugin model 6 in SPSS was used to analyse the mediating effects of ADL and depression on the relationship between chronic disease comorbidity and self-rated health among empty-nest elderly.

Results

The direct effect of chronic disease comorbidity on self-rated health among empty-nest elderly individuals was statistically significant (β=-1.2397, 95% CI: -1.4139~-1.0655), the separate mediating effect of ADL was statistically significant (β=-0.159, 95% CI: -0.278~-0.079), the separate mediating effect of depression was statistically significant (β=-0.160, 95% CI: -0.214~-0.115), and the chain mediating effect of ADL and depression was statistically significant (β=-0.073, 95% CI:-0.094~-0.056).

Conclusion

Chronic disease comorbidity can directly negatively impact the self-rated health status of empty-nest elderly individuals. It may also influence their self-rated health through the independent or chain mediating effects of activities of ADL and depression. Consequently, it is recommended that policy measures prioritise empty-nest elderly individuals within health interventions to reduce their risk of chronic disease comorbidity. This should involve establishing a comprehensive support system centred on functional assessment and psychological intervention, thereby improving the self-rated health status of this demographic.

Empty-nest elderly  /  Chronic disease comorbidity  /  Self-rated health  /  Activities of daily living  /  Depression
隋欣, 王文超, 宫云娜, 菅云龙, 宋立芹, 张晓林, 马勇. 日常生活活动能力和抑郁在慢性病共病对空巢老人自评健康的链式中介效应. 现代预防医学, 2026 , 53 (1) : 142 -147 . DOI: 10.20043/j.cnki.MPM.202507408
Xin SUI, Wen-chao WANG, Yun-na GONG, Yun-long JIAN, Li-qin SONG, Xiao-lin ZHANG, Yong MA. The chain mediating effects of activities of daily living and depression on self-rated health among empty-nest elderly with chronic disease comorbidity[J]. Modern Preventive Medicine, 2026 , 53 (1) : 142 -147 . DOI: 10.20043/j.cnki.MPM.202507408
Year 2026 volume 53 Issue 1
21
11
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doi: 10.20043/j.cnki.MPM.202507408
  • Receive Date:2025-07-23
  • Online Date:2026-11-02
  • Published:2026-01-10
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  • Received:2025-07-23
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    School of Management, Shandong Second Medical University, Weifang, Shandong 261053, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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