Full
Outline
This study aims to explore the association between the hemoglobin-to-red blood cell distribution width ratio (HRR) and the risk of diabetes mellitus (DM).
A total of 16 392 participants from the 2001—2020 National Health and Nutrition Examination Survey(NHANES) database were selected for this study. Logistic regression, subgroup analysis, and restricted cubic splin (RCS) analysis were applied to investigate the relationship between HRR and DM.
The mean HRR among the included participants was 0.27±0.98, with diabetic patients showing significantly lower HRR compared to the control group (P<0.001). Logistic regression analysis revealed that when HRR was modeled as a continuous variable, for each standard deviation increase in HRR, the risk of DM decreased by 11% (OR=0.89, 95% CI: 0.84-0.95). When HRR was treated as a categorical variable based on quartiles, the highest fourth quartile(Q4) consistently showed a significant reduction in DM risk compared to the lowest quartile (Q1) across all three models (OR<1). Subgroup analysis demonstrated that increased HRR was associated with a reduced risk of DM in most subgroups, with most P-values<0.05. The dose-response analysis indicated a linear negative correlation between HRR and the risk of DM(P-nonlinear=0.395).
HRR is associated with the risk of DM, and higher HRR levels are protective against the development of diabetes.
17
9
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
关闭全屏
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62662699(Operation and Technical Support)
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
