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Longtitudinal effects of informal caregiving on cognitive function among middle-aged and older adults in China
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Meng-qi ZHOU1, Lin HAN2, Si-ran CHEN1, Rui MA1, Xiao-yue JIANG1, Zi-yi YANG1, Yu-ling DU1, Ke-rui WANG1, Shao-hui SU1, Yi-nuo ZHOU1, Yan-fang YANG1
Modern Preventive Medicine | 2026, 53(6) : 1094 - 1098
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Modern Preventive Medicine | 2026, 53(6): 1094-1098
• Health and Social Behavior •
Longtitudinal effects of informal caregiving on cognitive function among middle-aged and older adults in China
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Meng-qi ZHOU1, Lin HAN2, Si-ran CHEN1, Rui MA1, Xiao-yue JIANG1, Zi-yi YANG1, Yu-ling DU1, Ke-rui WANG1, Shao-hui SU1, Yi-nuo ZHOU1, Yan-fang YANG1
Affiliations
  • Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University/West China Fourth Hospital, Chengdu, Sichuan 610041, China
Published: 2026-03-25 doi: 10.20043/j.cnki.MPM.202511222
Outline
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Objective

To examine the longitudinal association between informal caregiving and cognitive function among middle-aged and older Chinese adults, and to explore its heterogeneity.

Methods

Using five waves of longitudinal data (2011-2020) from the China Health and Retirement Longitudinal Study (CHARLS), this study included 4 841 adults aged 45 and above. Linear mixed-effects models were employed to analyze associations of informal caregiving and caregiving intensity with cognitive function, and investigated caregiving roles in relation to cognition, stratified by marital or cohabitation status.

Results

Compared to non-caregivers, caregivers demonstrated better performance in global cognition (β=0.039, 95% CI:0.001-0.076, P=0.043) and executive function (β=0.040, 95% CI:0.003-0.078, P=0.037). High-intensity caregiving was positively associated with global cognition (β=0.101, 95% CI:0.039-0.164, P=0.001), episodic memory (β=0.076, 95% CI: 0.014-0.138, P=0.016), and executive function (β=0.101, 95% CI:0.039-0.164, P=0.001). Moderate-intensity caregiving was associated with higher episodic memory scores (β=0.123, 95% CI: 0.002-0.244, P=0.047). Spousal caregivers had lower levels of global cognition (β=0.196, 95% CI: 0.351-0.040, P=0.014), whereas grandparent caregivers who were separated, divorced, or widowed showed superior episodic memory (β=0.163, 95% CI:0.013-0.314, P=0.033).

Conclusion

The impact of informal caregiving on cognitive function in middle-aged and older adults varies significantly based on the caregiving role, intensity, and sociodemographic characteristics. Future policies should provide differentiated support for various caregiver groups to optimize their health outcomes.

Informal caregiving  /  Cognitive function  /  Middle-aged and older adults  /  Caregiving intensity  /  Caregiver roles
周梦琦, 韩琳, 陈思燃, 马蕊, 蒋晓悦, 杨子乙, 杜昱玲, 王珂瑞, 苏绍辉, 周一诺, 杨艳芳. 中国中老年人非正式照护与认知功能的纵向关联研究. 现代预防医学, 2026 , 53 (6) : 1094 -1098 . DOI: 10.20043/j.cnki.MPM.202511222
Meng-qi ZHOU, Lin HAN, Si-ran CHEN, Rui MA, Xiao-yue JIANG, Zi-yi YANG, Yu-ling DU, Ke-rui WANG, Shao-hui SU, Yi-nuo ZHOU, Yan-fang YANG. Longtitudinal effects of informal caregiving on cognitive function among middle-aged and older adults in China[J]. Modern Preventive Medicine, 2026 , 53 (6) : 1094 -1098 . DOI: 10.20043/j.cnki.MPM.202511222
Year 2026 volume 53 Issue 6
21
11
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doi: 10.20043/j.cnki.MPM.202511222
  • Receive Date:2025-11-14
  • Online Date:2026-11-02
  • Published:2026-03-25
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  • Received:2025-11-14
Affiliations
    Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University/West China Fourth Hospital, Chengdu, Sichuan 610041, China
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表12种不同金属材料的力学参数
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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