To analyze the coupling and coordination relationship between the elderly population and the supply of medical resources in Guangdong Province from 2000 to 2020, and to provide insights for optimizing regional medical resource allocation, improving health and well-being among the elderly, and proactively addressing population aging.

Using data from population censuses and statistical yearbooks, the entropy method and the coupling coordination degree model were applied to evaluate the coupling coordination and matching degree of the elderly system and medical resource supply system.

From 2000 to 2020, the matching degrees of the elderly population and medical resource supply in Guangdong Province evolved from mild mismatch to basic match. Spatially, all cities had reached a minimally matched level by 2020, however, significant regional disparities remained. The Pearl River Delta and western Guangdong regions exhibited higher matching degrees than eastern and northern Guangdong.

The matching degree between the elderly population and medical resource supply in Guangdong has improved overall, though regional gaps remain. It is recommended that regions tailor medical resource allocation according to local aging trends, while proactively addressing the structural service needs of the elderly, such as chronic disease management and rehabilitation nursing, to enhance the precision and adaptability of resource matching.