Full
Outline
To analyze the epidemiological characteristics and influencing factors of repeated infections of hand-foot-and-mouth disease in Haikou City (2008-2024), and to provide reference for formulating prevention and control strategies.
Collect data through the national notifiable disease report system, Use descriptive statistics, logistic regression, and other methods for data analysis.
The recurrence rate of hand-foot-and-mouth disease in Haikou City (2008—2024) was 6.41%, and showed a fluctuating downward trend from 2016 onwards. The repeated infection epidemic season is from April to July and from September to November. The repeated infection rate in males (6.90%) is higher than that in females (5.62%). 95.18% of repeat infection patients are children aged 3 years and below, with repeat infection rates of 9.59%, 8.17%, 6.22%, and 4.95% in the age groups of <1、1-<2、2-<3 and 3-<4 years, respectively. The repeated infection rate among scattered children (7.32%) is higher than that of preschool children (4.14%) and students (0.96%). The repeated infection rate in rural areas (7.29%) is higher than that in urban areas (6.33%) and townships (5.50%). The median interval between repeated infections is 385 days, with 76.75% occurring within 2 years. The repeat infection rate of patients with severe symptoms (9.36%) is higher than that of patients with mild symptoms (6.39%). Male, 3 years old and under, scattered children and preschool children (compared with students), rural and urban areas (compared with towns), low incidence years, and severe first-time infections are risk factors for recurrent infections.
The repeated infection rate of hand-foot-and-mouth disease in Haikou City is showing a downward trend, but it is still necessary to continue to strengthen health education, pathogen monitoring and other prevention and control measures. The key prevention and control targets are scattered children aged 3 and below, and actively promote EV71 vaccination, which is conducive to controlling and reducing the occurrence of repeated infections.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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