Full
Outline
To identify the latent classes of health-related quality of life (HRQoL) and explore their influencing factors among patients with Kashin-Beck disease (KBD) in Xi’an.
A cluster sampling method was used to select 251 KBD patients diagnosed at stage I or above according to the “Diagnosis of Kashin-Beck Disease” (WS/T 207-2010) standard from Lintong District, Xi’an City. Surveys were conducted using a general information questionnaire and the Kashin-Beck Disease Quality of Life (KBDQOL) scale. Latent profile analysis (LPA) was employed to identify the latent classes of HRQoL, and multinomial logistic regression was used to explore the influencing factors.
The HRQoL of KBD patients was categorized into three distinct latent classes: the low HRQoL type (13.15%), the medium HRQoL-limited type (39.04%), and the high HRQoL-comprehensive type (47.81%). Regression analysis revealed that age, education level, living alone, disease severity, and disease duration were significant factors influencing the latent HRQoL profiles in KBD patients (all P<0.05). Patients with advanced age, long disease duration, severe disease, or illiteracy were more likely to belong to the “low HRQoL” profile.
Significant population heterogeneity in HRQoL exists among KBD patients in Xi’an. Targeted interventions should be implemented based on the characteristics of the identified latent classes, with particular attention given to alleviating the physical and mental burden of patients in the low and medium HRQoL types, in order to effectively enhance their HRQoL.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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