To investigate the role of social isolation in the long-term impact of adverse childhood experiences (ACEs) on depressive symptoms in middle-aged and older adults, and to provide empirical support for preventing and intervening in the negative effects of ACEs on mental health in this population.
Based on data from the 2014 life history survey and the 2018 and 2020 follow-up survey of the China Health and Retirement Longitudinal Study (CHARLS), a total of 12 695 middle-aged and older adults aged ≥45 years were included. ACEs were derived from the 2014 data, social isolation from the 2018 data, and depressive symptoms from the 2020 data. The relationships among social isolation, ACEs, and depressive symptoms were examined using independent samples t-tests, chi-square tests, and Pearson correlation analysis. The mediating effect of social isolation between ACEs and depressive symptoms was analyzed through mediation models, Sobel tests, and bootstrap tests.
ACEs showed a significant positive correlation with depressive symptoms (β=0.618, P<0.001). Path analysis revealed that social isolation partially mediated the association between ACEs and depressive symptoms. Specifically, ACEs positively predicted social isolation (β=0.026, P<0.001), and social isolation positively predicted depressive symptoms (β=0.913, P<0.001). Both Sobel and Bootstrap tests confirmed the robustness of this mediating effect. The influence of ACEs and social isolation on depressive symptoms was consistent across different genders and age groups within the middle-aged and elderly population.
ACEs can directly or indirectly influence depressive symptoms in middle-aged and older adults through the mediating effect of social isolation. Relevant social departments should implement life-course intervention strategies, including preventing ACEs, providing psychological counseling, and building social support networks, to alleviate depression issues among middle-aged and older adults.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |