Full
Outline
To compare and analyze the reported incidence of adverse events following immunization (AEFI) before and after the adjustment of the poliomyelitis immunization schedule in Tianjin.
We obtained AEFI case data and the vaccine doses for poliomyelitis vaccine from the Immunization Program Information System from May 2016 to December 2019(pre-adjustment) and from January 2020 to September 2024 (post-adjustment). Reported incidence rates were calculated and compared between the periods.
Before the adjustment, the reported incidence rates of AEFI in Tianjin were 37.00 per 100 000 doses for bOPV and 50.52 per 100 000 doses for IPV, the incidence rates of common adverse reactions were 30.06 per 100 000 doses (bOPV) and 43.87 per 100 000 doses (IPV), while those of abnormal reactions were 5.26 per 100 000 doses(bOPV) and 5.32 per 100 000 doses (IPV). After the adjustment, the reported incidence rates of AEFI declined to 26.70 per 100 000 doses for bOPV and 33.13 for IPV per 100 000 doses, the incidence rates of common adverse reactions were 21.10 per 100 000 doses (bOPV) and 28.24 per 100 000 doses (IPV), and abnormal reactions were 4.62 per 100 000 doses (bOPV) and 3.57 per 100 000 doses (IPV). There were statistically significant differences in the reported incidence of AEFI before and after the adjustment (χ2=7.45, P<0.01; χ2=24.20, P<0.01).
After the adjustment to the immunization strategy of polio vaccine in Tianjin, AEFI reporting rates decreased, with rare serious adverse reactions and favorable overall safety.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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