Full
Outline
To investigate the prevalence of human papillomavirus(HPV) infection among females in Nanhai District,Foshan City, and elucidate the distribution patterns of HPV genotypes across different cervical lesions.
HPV genotyping results from 28 592 female patients who underwent physical examinations or medical consultations at the Seventh Affiliated Hospital of Southern Medical University between 2020 and 2024 were collected. Statistical analyses were conducted on HPV subtype infection status, age distribution, and clinical diagnosis.
From 2020 to 2024, HPV infection among females in Nanhai District, Foshan City, exhibited a distinct U-shaped age distribution (higher infection rates in the ≤20 and ≥61 age groups), with high-risk types predominating. High-risk HPV types 52, 16, and 58 were identified as the primary pathogenic variants in this region, with HPV16 infection rates showing a significant increase correlating with lesion severity.The 9-valent vaccine could cover 78.26% of cervical cancer-associated HPV genotypes in this region, but its overall HPV infection coverage rate was 42.80%.
The HPV infection pattern among females in Nanhai District, Foshan City from 2020 to 2024 demonstrated significant age-related disparities, with a U-shaped infection rate trend over the five-year period. It is recommended to enhance screening and education for age-eligible populations, strengthen surveillance and vaccine promotion, and continuously monitor the epidemiological trends of non-vaccine-covered high-risk types (e.g., HPV 51, 68, 39).
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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