To investigate the association between Tsampa consumption and biological age acceleration.
Utilizing baseline data from the China Multi-Ethnic Cohort study (CMEC), a composite biomarker-based biological age was constructed using the Klemera-Doubal Method (Biological age based on Klemera and Doubal’s method, KDM-BA). Biological aging was quantified as the difference between KDM-BA and chronological age. Tsampa consumption information was obtained via a Food Frequency Questionnaire (FFQ). Weekly intake was calculated based on consumption frequency and gram weight, and participants were categorized into four groups: non-consumption, low, moderate, and high, based on the 25th and 75th percentiles. Multiple linear regression was employed to analyze the association between Tsampa consumption and biological age acceleration. Stratified analyses were conducted using sex, age, smoking, alcohol consumption, and BMI as stratification factors.
A total of 4 335 participants were included. Compared to non-consumption, Tsampa consumption showed a negative association with biological age acceleration(β=-0.66,95% CI:-0.99- -0.327). A statistically significant association was found for moderate Tsampa consumption (700-1 400 grams)(β=-1.24,95% CI: -2.04- -0.44). Associations for low and high consumption levels were not statistically significant [Low:(β=0.11, 95% CI:-0.67-0.88); High:(β=-0.39,95% CI:-1.37-0.60)]. The protective effect of Tsampa consumption against biological age acceleration was stronger in males than in females [Males: (β=-0.83, 95% CI: -1.24- -0.43); Females:(β=-0.61,95% CI:-1.08- -0.13)].
Tsampa consumption is negatively associated with biological age acceleration, suggesting its potential beneficial role in promoting healthy aging in the Tibetan region.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |