Home Journals Articles Updates About
CN
image
收藏切换
The mediating effect of depression in older adults between cardiometabolic multimorbidity and disability status
收藏切换
Xia HUANG1, 2, 3, Shi-ting ZHANG1, 2, 3, Chun-ying LIU1, 2, 3, Rui-xin KANG1, 2, 3, Hao QIN1, 2, 3
Modern Preventive Medicine | 2025, 52(20) : 3656 - 3661
Less
收藏切换
Modern Preventive Medicine | 2025, 52(20): 3656-3661
• Epidemiology and Statistical Methods Advances •
The mediating effect of depression in older adults between cardiometabolic multimorbidity and disability status
Full
Xia HUANG1, 2, 3, Shi-ting ZHANG1, 2, 3, Chun-ying LIU1, 2, 3, Rui-xin KANG1, 2, 3, Hao QIN1, 2, 3
Affiliations
  • School of Public Health, Shandong Second Medical University, Weifang, Shandong 261053, China
Published: 2025-10-25 doi: 10.20043/j.cnki.MPM.202504257
Outline
收藏切换
Objective

To explore the mediating role of depression between cardiometabolic multimorbidity (CMM) and disability status among older adults, and to provide a theoretical basis for the prevention and management of disability among the elderly.

Methods

Based on cross-sectional data from the China Health and Retirement Longitudinal Study (CHARLS) in 2020, 8 270 elderly individuals aged≥60 years were included. Correlation and mediation analyses were conducted to examine the associations among depression, CMM and disability. The PROCESS 4.1 macro was employed to test the mediating effect of depression, and the mediating variables were verified using the Bootstrap method.

Results

The detection rate of disability was 19.1%. After controlling for confounders, both CMM and depression were positively correlated with disability(r=0.142, r=0.209, P<0.001). CMM significantly predicted disability status of the elderly (β=0.414, t=13.040, P<0.001), with depression accounting for 17.39% of the total effect (β=0.072, 95% CI:0.056-0.091).

Conclusion

Cardiometabolic multimorbidity can directly or indirectly influence the disability status through the mediating role of depression. Relevant authorities should enhance public awareness campaigns and implement integrated intervention strategies addressing both physiological and psychological aspects to mitigate disability risk in older adults.

Older adults  /  Cardiometabolic multimorbidity  /  Depression  /  Disability status  /  Mediating effect
黄霞, 张诗婷, 刘春莹, 康睿欣, 秦浩. 老年人抑郁在心脏代谢性共病和失能状况之间的中介效应. 现代预防医学, 2025 , 52 (20) : 3656 -3661 . DOI: 10.20043/j.cnki.MPM.202504257
Xia HUANG, Shi-ting ZHANG, Chun-ying LIU, Rui-xin KANG, Hao QIN. The mediating effect of depression in older adults between cardiometabolic multimorbidity and disability status[J]. Modern Preventive Medicine, 2025 , 52 (20) : 3656 -3661 . DOI: 10.20043/j.cnki.MPM.202504257
Appendix
Less
Year 2025 volume 52 Issue 20
55
26
Cite this Article
BibTeX
Article Info
doi: 10.20043/j.cnki.MPM.202504257
  • Receive Date：2025-04-13
  • Online Date：2026-10-29
  • Published：2025-10-25
Article Data
Affiliations
History
  • Received：2025-04-13
Funding
Affiliations
    School of Public Health, Shandong Second Medical University, Weifang, Shandong 261053, China
References
Share
https://castjournals.cast.org.cn/joweb/xdyfyx/EN/10.20043/j.cnki.MPM.202504257
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62662699(Operation and Technical Support)
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House