To analyze the changing trends in gonorrhea incidence in China from 2005 to 2024, evaluate the influence of age, period, and birth cohort factors, and provide a basis for the development of gonorrhea prevention and control strategies.
Gonorrhea incidence data from 2005 to 2025 were extracted from the China Public Health Science Data Center and the China Health Statistical Yearbook. A Joinpoint regression model was used to calculate the annual percentage change (APC) and the average annual percentage change (AAPC) to describe the incidence trends. An age-period-cohort model was constructed to evaluate the effects of age, period, and birth cohort on the incidence rate.
From 2005 to 2024, the overall incidence rate of gonorrhea in China showed a declining trend (AAPC=-3.47%, P<0.001). The age effect followed an “S-shaped” curve, with an increasing trend in the 15-29-year age group and decreasing trends in the 0 to 14-year and 30-84-year age groups. The period effect decreased over the years. The cohort effect generally showed an “M-shaped” decline, with an increasing trend from 1925-1929, a fluctuating decline from 1930-1994, a rapid increase from 1995—2009 reaching a peak, and a rapid decline from 2010-2020.
The overall incidence rate of gonorrhea in China is declining. Attention should be focused on high-incidence areas such as the Zhejiang Province and Yunnan Province, as well as key populations in the 15-34-year age group. Health education on gonorrhea prevention and control should be strengthened, and active screening in high-risk areas and among key populations should be promoted to achieve early diagnosis and early treatment.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |