To analyze the changes and influencing factors of female health literacy level in Nanchang, and to provide reference for intervention in female health literacy.

Based on the health literacy monitoring of residents in Nanchang from 2018 to 2023, analyze the data of 10 034 women in the effective sample. Conduct inter-group difference comparisons and influencing factor analyses on the health literacy levels of women with different characteristics by using the χ² test and Logistic regression model. And analyze the changes in the health literacy of women in Nanchang City using the χ² trend test.

From 2018 to 2023, the level of female health literacy in Nanchang showed rising year by year, increased from 17.87% to 30.80%. Health knowledge and concept as well as safety and first aid ranked first in three aspects and six dimensions of health literacy. The factors affecting female health literacy in Nanchang included regions, age, education, occupation and marriage. The health literacy level of urban women was 1.249 times higher than that of rural women (OR=1.249, 95%CI: 0.934-1.669; The health literacy level of women aged 35-44 was 93.5% higher than that of women aged 15-24; The health literacy level of women with junior college and above (OR=15.851, 95% CI: 12.525-20.060) was 15.851 times higher than that of women with primary school and below; The health literacy level of female civil servants/teachers and other employees of public institutions (OR=0.373, 95%CI: 0.252-0.553) and female farmers (OR=0.368, 95%CI: 0.231-0.585) were significantly lower than female medical staff; Unmarried women had a higher level of health literacy than married women by 45.5% (OR=0.545, 95%CI: 0.332-0.896).

The level of female health literacy in Nanchang has been improved. In the future, infectious and chronic disease prevention and basic medical literacy should be the key content. Focusing on key population such as women of farmers, the elderly, lower education level and low-income, targeted health education and promotion activities will be innovatively carried out to popularize healthy lifestyles and skills.