To explore the mediating effect of depression between life self-care ability and frailty.
Based on data from the China Health and Retirement Longitudinal Study (CHARLS), Pearson correlation analysis, linear regression model and Bootstrap repeated sampling method were used to analyse the relationships and mediating effects between activity of daily living, depression and frailty.
A total of 1 554 middle-aged and elderly people aged 45 years or older were included. The prevalence of debility was 14.1%, with a self-care score of 5.9±0.4 and a depression score of 9.4±6.0. Activity of daily living was significantly negatively correlated with depression and frailty (r=-0.14, r=-0.23, both P<0.001), and depression and frailty were positively correlated (r=0.34, P< 0.001). Activity of daily living (β=-0.164, P<0.001) and depression (β=0.013, P< 0.001) were influences on frailty, and depression partially mediated the relationship between activity of daily living and frailty, with a mediating effect of 12.17%.
Depression reduces the ameliorative effect of self-care ability on debility.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |