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To analyze suspected adverse events following immunization (AEFI) of poliomyelitis vaccination (PV) in Anhui Province from 2020 to 2023.
Data on adverse events following immunization (AEFI) were collected through the AEFI monitoring module of the Chinese Disease Prevention and Control Information System. These included cases related to the bivalent oral poliovirus vaccine (bOPV), inactivated poliomyelitis vaccine made from Sabin strains (sIPV), inactivated poliovirus vaccine (IPV), and the combined diphtheria, tetanus, acellular pertussis, inactivated poliovirus, and Haemophiles influenza type b vaccine (DTaP-IPV-Hib). The number of vaccine doses administered was obtained from the Anhui Immunization Program Information Management System. Descriptive epidemiological methods were used to analyze the incidence and characteristics of AEFI reports.
A total of 3 036 cases of AEFI related to poliomyelitis vaccination were reported in Anhui Province from 2020 to 2023, with an overall incidence rate of 38.37 per 100 000 doses. The incidence rates for bOPV, IPV-Sabin, IPV-Salk, and DTaP-IPV-Hib were 17.47, 47.86, 33.29, and 82.11 per 100 000 doses, respectively. General reactions accounted for 94.57% of cases, while abnormal reactions constituted 4.97%. The male-to-female ratio was 1.31:1. Among general reactions, the incidence rates for high fever (axillary temperature ≥ 38.6°C), local swelling (diameter > 2.5 cm), and local induration (diameter > 2.5 cm) were 8.67, 7.22, and 4.41 per 100 000 doses, respectively. For abnormal reactions, the incidence rates for allergic rashes and other diseases were 1.43 and 0.48 per 100 000 doses, respectively.
From 2020 to 2023,AEFI related to poliomyelitis vaccination in Anhui Province were predominantly general reactions, with abnormal reactions being rare.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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