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Study on the effect of new low-protein enteral nutritional preparation on patients with chronic kidney disease
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Jian-kui GUO1, Zi-qi ZHOU2, Yuan LIU2, Yi CHEN3, Yue-yang HUANG3, Wen HU1, 2
Modern Preventive Medicine | 2024, 51(3) : 564 - 571
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Modern Preventive Medicine | 2024, 51(3): 564-571
Clinical Medicine and Prevention
Study on the effect of new low-protein enteral nutritional preparation on patients with chronic kidney disease
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Jian-kui GUO1, Zi-qi ZHOU2, Yuan LIU2, Yi CHEN3, Yue-yang HUANG3, Wen HU1, 2
Affiliations
  • Department of Nutrition and Food Hygiene, West China School of Public Health, Sichuan University/West China Fourth Hospital, Chengdu, Sichuan 610041, China
Published: 2024-02-10 doi: 10.20043/j.cnki.MPM.202306139
Outline
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Objective

To explore the effect of a new type of low-protein enteral nutrition on the nutritional status of patients with chronic kidney disease in stage 3-4 under the guidance of individualized diet.

Methods

Sixty follow-up outpatients in West China Hospital of Sichuan University were randomly divided into the experimental group and the control group. The two groups were followed up on intervention day 0, day 45, and day 90. According to the principle of intentional analysis, the generalized estimation equation was used to analyze the between-group differences, time change trend, and interaction effect, and the principle of data analysis in accordance with the scheme was used to further verify the stability of results.

Results

There was no significant difference in nutritional adequacy, clinical effectiveness, and anthropometric indexes between the test group and the control group (P > 0.05). During the intervention period, when the energy intake was stable, the intake of protein (χ2=17.680, P<0.001) and sodium salt (χ2=21.427, P<0.001) decreased significantly, while the total protein (χ2=18.075, P<0.001), calcium (χ2=9.438, P=0.009), phosphorus (χ2=13.866, P=0.001), and uric acid (χ2=9.005, P=0.011) fluctuated within the normal range. The results of data analysis in accordance with the scheme were basically consistent with those of intentionality analysis. Only the time change trend of upper arm muscle circumference (χ2=6.435, P=0.040) and the comparison of energy ratio between groups(χ2=4.478, P=0.034) were significantly different.

Conclusion

The new low-protein enteral nutrition preparation is not inferior to the total nutritional formula food for special medical use in improving the nutritional status of patients and delaying the progression of the disease. The use of enteral nutrition under dietary guidance is beneficial to the clinical nutrition management of

Renal insufficiency  /  Chronic  /  Nutritional status  /  Dietary guidance  /  Low-protein diet  /  Compliance  /  Enteral nutrition preparation  /  Formula food for special medical purposes
Jian-kui GUO, Zi-qi ZHOU, Yuan LIU, Yi CHEN, Yue-yang HUANG, Wen HU. Study on the effect of new low-protein enteral nutritional preparation on patients with chronic kidney disease[J]. Modern Preventive Medicine, 2024 , 51 (3) : 564 -571 . DOI: 10.20043/j.cnki.MPM.202306139
Year 2024 volume 51 Issue 3
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Article Info
doi: 10.20043/j.cnki.MPM.202306139
  • Receive Date:2023-06-09
  • Online Date:2026-03-19
  • Published:2024-02-10
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History
  • Received:2023-06-09
Funding
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    Department of Nutrition and Food Hygiene, West China School of Public Health, Sichuan University/West China Fourth Hospital, Chengdu, Sichuan 610041, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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