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To systematically evaluate the post-market safety of human papilloma virus vaccine in Jiangxi province．
The doses number of HPV administered from 2017 to 2022 wascollected from all the vaccination institutions, and theadverse events followingimmunization（AEFI）cases were collected through the AEFI Surveillance Module of Chinese Disease Control and Prevention Information System. Using descriptive statistics, the incidences and epidemiological characteristics were estimated．
81 AEFI cases of HPV were reported from 2017 to 2022，and the incidence was 3.38 per 100 000 doses. Moreover, the incidence of HPV2, HPV4 and HPV9 were 3.21, 3.38 and 3.84 per 100 000 doses, respectively. A totalof 71.60% cases were 20-39 years old and 75.31%occurred in 2 days after inoculation. 59.26% were common adverse reactions. Most rare vaccine reactions were allergic rashes, and the reported incidence was 0.50 per 100 000 doses.
The human papilloma virus vaccine has acceptable safety profile in Jiangxi. The sensitivity of monitoring system needs to be further improved.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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