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Associations of lifestyle scores with nonalcoholic fatty liver disease
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Ying CHEN, Liu-hong XU, Ying-ying MAO, Ding YE
Modern Preventive Medicine | 2024, 51(4) : 742 - 747
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Modern Preventive Medicine | 2024, 51(4): 742-747
• Disease Control and Prevention •
Associations of lifestyle scores with nonalcoholic fatty liver disease
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Ying CHEN, Liu-hong XU, Ying-ying MAO, Ding YE
Affiliations
  • Department of PublicHealth, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China
Published: 2024-02-25 doi: 10.20043/j.cnki.MPM.202310283
Outline
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Objective

To analyze and explore the association between lifestyle scores and the risk of developing nonalcoholic fatty liver disease (NAFLD) in the United States (US) population, and to provide new ideas for the prevention and treatment of NAFLD.

Methods

The samples of this study were collected from the 2007-2018 US National Health and Nutrition Examination Survey (NHANES) database. Logistic regression analysis was employed to assess the impact of healthy lifestyle and NAFLD. Further stratified analyses were conducted to investigate potential differences across gender, age, ethnicity, marital status, and education levels.

Results

A total of 4 105 participants were included in this study, comprising 1 284 individuals with NAFLD (24.64%) and 2 821 individuals without NAFLD (75.36%). Compared to low lifestyle score, individuals with moderate (OR=0.372, 95% CI: 0.25-0.56, P=9.15×10-6) and high lifestyle score (OR=0.091, 95% CI: 0.06-0.14, P=1.50×10-17) had a lower risk of developing NAFLD. Stratified analyses revealed that this effect was more pronounced among males and individuals aged 60 and above.

Conclusion

Healthy lifestyle is associated with a decreased risk of NAFLD, and improving lifestyle score can be effective in preventing and treating NAFLD.

Lifestyle score  /  NAFLD  /  NHANES
Ying CHEN, Liu-hong XU, Ying-ying MAO, Ding YE. Associations of lifestyle scores with nonalcoholic fatty liver disease[J]. Modern Preventive Medicine, 2024 , 51 (4) : 742 -747 . DOI: 10.20043/j.cnki.MPM.202310283
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Article Info
doi: 10.20043/j.cnki.MPM.202310283
  • Receive Date：2023-10-20
  • Online Date：2026-03-19
  • Published：2024-02-25
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History
  • Received：2023-10-20
Affiliations
    Department of PublicHealth, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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