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To investigate the death trend of HIV/AIDS patients in Shandong Province from 2013 to 2022, andto explore the related influencing factors.
A total of 25 181 HIV/AIDS patients living in Shandong Province from 2013 to 2022 were selected as the study objects, demographic characteristics, antiretroviral therapy and causes of death were collected. Study objects were divided into three groups: survival, AIDS-related death and non-AIDS-related death. Kruskal-Wallis test and χ2 test were conducted for inter group comparison, Joinpoint regression model was used to analyze the trend change of mortality, and unordered multicategorical logistic regression was used to analyze HIV/AIDS death and its influencing factors.
From 2013 to 2022, a total of 1 187 HIV/AIDS patients deaths were reported in Shandong Province, among which AIDS-related deaths accounted for 34.63% and non-AIDS-related deaths accounted for 65.37%. The mortality rates showed a decreasing trend (APC was -13.58, -20.29, and -9.67, respectively, all P<0.05). Unordered multicategorical logistic regression analysis showed that the time from diagnosis to ART initiation greater than 30 days, WHO clinical stage Ⅱ, Ⅲ, and Ⅳ were the risk factors for AIDS-related death of HIV/AIDS patients, and the OR (95% CI) values were 1.74(1.41-2.16), 1.93(1.38-2.70), 2.61(1.87-3.63) and 4.81(3.71-6.23); the time from diagnosis to ART initiation greater than 30 days, male, farmer and heterosexual transmission were the risk factors for non-AIDS-related death of HIV/AIDS patients, with OR (95% CI) values of 2.10(1.79-2.46), 1.75(1.38-2.20), 1.60(1.28-2.01), and 1.75(1.48-2.08).
From 2013 to 2022, the case fatality rate of HIV/AIDS patients in Shandong Province has shown a downward trend after the start of ART, the age of death increased, and the case fatality rate of non-AIDS-related deaths is generally higher than that of AIDS-related deaths. There are differences in the influencing factors for AIDS-related and non-AIDS-related deaths, and targeted interventions should be developed.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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