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To analyze the quality of life (QoL) status and influencing factors among human immunodeficiency virus/hepatitis C virus (HIV/HCV) co-infected individuals in Yunnan using structural equation modeling (SEM), providing empirical evidence for improving their QoL.
A cross-sectional survey was conducted from June to September 2024 using convenience sampling in Dehong, Dali, Kunming, and Lincang. Data on socio-demographics, social support, and depression were collected, with QoL assessed using the SF-36 scale. SEM was constructed using AMOS 24.0.
The mean QoL score (65.91±21.71) was lower than Chinese norms. SEM revealed direct effects on physical health from monthly income (β=0.18, 95%CI: 0.09-0.29), occupation (β=-0.09, 95%CI: -0.18 to -0.01), HIV diagnosis duration (β=-0.11, 95%CI: -0.19 to -0.02), HIV knowledge (β=-0.36, 95%CI: -0.47 to -0.27), HCV knowledge (β=-0.14, 95%CI: -0.22 to -0.05), social support (β=0.14, 95%CI: 0.02-0.28),and depression (β=-0.34, 95%CI: -0.42 to -0.24). Monthly income (β=-0.17, 95%CI: -0.27 to -0.06), HIV knowledge (β=0.14,95%CI: 0.05-0.24), and social support (β=-0.25, 95%CI: -0.36 to -0.11) indirectly affected physical/mental health through depression.
HIV/HCV co-infected individuals in Yunnan exhibit poor QoL. Interventions should enhance mental health support and social assistance, particularly targeting those with low income, unemployment, long HIV diagnosis duration, and limited disease knowledge to improve treatment adherence and self-management.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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