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To describe the incidence of adverse birth outcomes in AIDS-infected parturients in Anhui province, and to analyze the effects of antiretroviral treatment, complications during pregnancy, and other socio-demographic factors on adverse birth outcomes.
Information of all HIV-infected mothers and their newborns in Anhui province from 2011 to 2023 was collected from the National Direct Reporting Information System for the Prevention of mother-to-child transmission of AIDS, Syphilis, and Hepatitis B. The risk factors of adverse birth outcomes among HIV-infected mothers were analyzed by Chi-square test and multiple logistic regression analysis.
In Anhui Province, the incidence of at least one adverse birth outcome, preterm birth, low birth weight, stillbirth/neonatal death, and birth defect was 13.9%, 9.0%, 8.2%, 2.6%, and 0.3%, respectively. The risk of total adverse birth outcomes was higher in AIDS-infected women with higher education (OR=2.770, 95% CI: 1.043-7.354), farmers (OR=2.877, 95% CI: 1.454-5.692), and moderate to severe anemia (OR=4.053, 95% CI: 1.411-11.643). Higher education level (OR=3.815, 95% CI: 1.145-12.705), occupation as a farmer (OR=2.763, 95% CI: 1.228-6.218), pregnancy combined with diabetes (OR=2.546, 95% CI: 1.025-6.325) promoted premature birth; The risk of low birth weight was higher in farmers (OR=2.626, 95% CI: 1.108-6.224), taking anti-HIV drugs (OR=12.949, 95% CI: 1.209-138.725), moderate to severe anemia (OR=4.281, 95% CI: 1.288-14.224) and pregnancy-induced hypertension (OR=4.880, 95% CI: 1.207-19.735). First marriage/divorce/widowhood (OR=0.264, 95% CI: 0.108-0.646) was associated with a lower risk of low birth weight than unmarried/cohabiting individuals. The effect of syphilis in pregnancy on stillbirth/neonatal death was statistically significant (OR=32.795, 95% CI: 1.178-913.003).
Further interventions are needed to improve pregnancy outcomes for women living with HIV.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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