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Correlation between Serum Uric acid to high-density lipoprotein cholesterol ratio and chronic kidney disease in middle-aged and elderly population in China
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Zhou-yu LU1, 2, Rui-peng WU2, 3, Meng-jun ZHANG1, 2, Wen-yuan LI1, 2
Modern Preventive Medicine | 2024, 51(14) : 2507 - 2512
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Modern Preventive Medicine | 2024, 51(14): 2507-2512
Epidemiology and Statistical Methods Advances
Correlation between Serum Uric acid to high-density lipoprotein cholesterol ratio and chronic kidney disease in middle-aged and elderly population in China
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Zhou-yu LU1, 2, Rui-peng WU2, 3, Meng-jun ZHANG1, 2, Wen-yuan LI1, 2
Affiliations
  • School of Public Health,Southern Medical University,Guangzhou, Guangdong 510515,China
Published: 2024-07-25 doi: 10.20043/j.cnki.MPM.202402275
Outline
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Objective

To investigate the correlation between UHR and CKD in middle-aged and elderly population.

Methods

The data of this study was obtained from 2015 China Health and Retirement Longitudinal Survey(CHARLS).A total of 9 204 people≥45 years old were included.Multivariate Logistics regression analysis was used to analyze the correlation between UHR and CKD.The receiver operating characteristic(ROC)curves was used to analyze the predictive value of UHR for the risk of CKD.

Results

The subjects who we included have the mean age of 60.78±9.32 years with the prevalence of CKD of 3.97%.The odd rations for the highest quartile group (Q4 group)of UHR was increased for CKD(OR=12.01, 95%CI:7.50-20.00).ROC curve analysis showed that the area under the ROC Curve(AUC) for UHR predicting CKD for middle-aged and elderly population was 0.76(95%CI:0.73-0.78),the AUC for UHR predicting CKD for male group was 0.74(95%CI:0.70-0.77)and the AUC for UHR predicting CKD for female group was 0.77(95%CI:0.73-0.81).

Conclusion

There was a positive correlation between the increased UHR level and risk of CKD among the middle-aged and elderly population in China.UHR might serve as a risk factor and demonstrated good predictive value for CKD in the middle-aged and elderly population in China.

Chronic kidney disease  /  Serum Uric acid  /  Serum High density lipoprotein cholesterol  /  China Health and Retirement Longitudinal Study  /  Forecasting  /  Logistic regression
Zhou-yu LU, Rui-peng WU, Meng-jun ZHANG, Wen-yuan LI. Correlation between Serum Uric acid to high-density lipoprotein cholesterol ratio and chronic kidney disease in middle-aged and elderly population in China[J]. Modern Preventive Medicine, 2024 , 51 (14) : 2507 -2512 . DOI: 10.20043/j.cnki.MPM.202402275
Year 2024 volume 51 Issue 14
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Article Info
doi: 10.20043/j.cnki.MPM.202402275
  • Receive Date:2024-02-28
  • Online Date:2026-03-18
  • Published:2024-07-25
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  • Received:2024-02-28
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    School of Public Health,Southern Medical University,Guangzhou, Guangdong 510515,China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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