To investigate the impact of serum vitamin C levels on metabolic syndrome in adults based on NHANES 2017-2018 data.
A total of 2 094 adults from the NHANES 2017-2018 dataset were included, with serum vitamin C levels as the primary exposure variable and metabolic syndrome, diagnosed according to the standards of the International Diabetes Federation and the American Heart Association, as the outcome variable. A multivariable logistic regression model was utilized to analyze the association between these variables, with subgroup analyses conducted for gender, age, and other factors.
The risk of metabolic syndrome decreased with increasing serum vitamin C levels (P trend < 0.001). Compared to the lowest quartile of serum vitamin C levels (Q1), the highest quartile (Q4) exhibited a relatively lower risk of metabolic syndrome (OR=0.66, 95%CI:0.48-0.92). Subgroup analyses by gender and age indicated a more pronounced protective effect in women and individuals under 50 years of age; women in the highest serum vitamin C level group had a lower risk of metabolic syndrome (Q4 group: OR=0.42,95%CI: 0.28-0.63). Additionally, individuals under 50 years of age in the second and highest serum vitamin C level groups also had reduced risks of metabolic syndrome (Q3 group: OR=0.41, 95%CI: 0.25-0.68; Q4 group: OR=0.19, 95%CI: 0.13-0.30).
This study suggests that higher serum vitamin C levels may be associated with a lower risk of metabolic syndrome in adults, with a more pronounced effect observed in women and individuals under 50 years of age.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |