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Study on the impact of serum vitamin C levels on metabolic syndrome in adults
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Lv-ning ZHANG1, Xiao-yu WANG2, Meng-xue CHEN2, Rui-rui LI1, Jing-yuan XIONG1, Guo CHENG2, 3
Modern Preventive Medicine | 2025, 52(5) : 795 - 800
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Modern Preventive Medicine | 2025, 52(5): 795-800
Epidemiology and Statistical Methods
Study on the impact of serum vitamin C levels on metabolic syndrome in adults
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Lv-ning ZHANG1, Xiao-yu WANG2, Meng-xue CHEN2, Rui-rui LI1, Jing-yuan XIONG1, Guo CHENG2, 3
Affiliations
  • West China School of Public Health, Sichuan University / West China Fourth Hospital, Chengdu, Sichuan 610041, China
Published: 2025-03-10 doi: 10.20043/j.cnki.MPM.202411508
Outline
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Objective

To investigate the impact of serum vitamin C levels on metabolic syndrome in adults based on NHANES 2017-2018 data.

Methods

A total of 2 094 adults from the NHANES 2017-2018 dataset were included, with serum vitamin C levels as the primary exposure variable and metabolic syndrome, diagnosed according to the standards of the International Diabetes Federation and the American Heart Association, as the outcome variable. A multivariable logistic regression model was utilized to analyze the association between these variables, with subgroup analyses conducted for gender, age, and other factors.

Results

The risk of metabolic syndrome decreased with increasing serum vitamin C levels (P trend < 0.001). Compared to the lowest quartile of serum vitamin C levels (Q1), the highest quartile (Q4) exhibited a relatively lower risk of metabolic syndrome (OR=0.66, 95%CI:0.48-0.92). Subgroup analyses by gender and age indicated a more pronounced protective effect in women and individuals under 50 years of age; women in the highest serum vitamin C level group had a lower risk of metabolic syndrome (Q4 group: OR=0.42,95%CI: 0.28-0.63). Additionally, individuals under 50 years of age in the second and highest serum vitamin C level groups also had reduced risks of metabolic syndrome (Q3 group: OR=0.41, 95%CI: 0.25-0.68; Q4 group: OR=0.19, 95%CI: 0.13-0.30).

Conclusion

This study suggests that higher serum vitamin C levels may be associated with a lower risk of metabolic syndrome in adults, with a more pronounced effect observed in women and individuals under 50 years of age.

Serum vitamin C  /  Metabolic syndrome  /  NHANES  /  Correlation study
Lv-ning ZHANG, Xiao-yu WANG, Meng-xue CHEN, Rui-rui LI, Jing-yuan XIONG, Guo CHENG. Study on the impact of serum vitamin C levels on metabolic syndrome in adults[J]. Modern Preventive Medicine, 2025 , 52 (5) : 795 -800 . DOI: 10.20043/j.cnki.MPM.202411508
Year 2025 volume 52 Issue 5
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Article Info
doi: 10.20043/j.cnki.MPM.202411508
  • Receive Date:2024-11-27
  • Online Date:2026-03-18
  • Published:2025-03-10
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  • Received:2024-11-27
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    West China School of Public Health, Sichuan University / West China Fourth Hospital, Chengdu, Sichuan 610041, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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